Results 81 to 90 of about 3,919,417 (298)
Existence of global weak solutions to some regularized kinetic models for dilute polymers [PDF]
, 2007 Published ...
Sueli, E, Suli, E, Barrett, JW
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Weak solutions for parabolic equations with p(x)-growth
Electronic Journal of Differential Equations, 2016 In this article we study nonlinear parabolic equations with p(x)-growth in the space $W^{1,x}L^{p(x)}(Q)\cap L^\infty(0,T; L^2(\Omega))$. By using the method of parabolic regularization, we prove the existence and uniqueness of weak solutions for the
Ning Pan, Binlin Zhang, Jun Cao
doaj
On a class of superlinear nonlocal fractional problems without Ambrosetti–Rabinowitz type conditions
Electronic Journal of Qualitative Theory of Differential Equations, 2019 In this note, we deal with the existence of infinitely many solutions for a problem driven by nonlocal integro-differential operators with homogeneous Dirichlet boundary conditions \begin{equation*} \begin{cases} -\mathcal{L}_{K}u=\lambda f(x,u), &
Qing-Mei Zhou
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Weak solutions for a viscous p-Laplacian equation
Electronic Journal of Differential Equations, 2003 In this paper, we consider the pseudo-parabolic equation $ u_t-kDelta u_t=mathop{ m div}(| abla u|^{p-2} abla u)$. By using the time-discrete method, we establish the existence of weak solutions, and also discuss the uniqueness.
Changchun Liu
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
AxiomsA system of nonlinear wave equations in viscoelasticity with variable exponents is considered. It is assumed that the kernel included in the integral term of the equations depends on both the time and the spatial variables.
Mouhssin Bayoud +4 more
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On the nonuniqueness of weak solution of the Euler equation [PDF]
Communications on Pure and Applied Mathematics, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources