Results 111 to 120 of about 4,087,279 (255)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Scaling-Invariant Serrin Criterion via One Row of the Strain Tensor for the Navier–Stokes Equations

open access: yesMathematics
Miller (Arch. Rational Mech. Anal., 2020) posed the question of whether it is possible to prove the Navier–Stokes regularity criterion using only one entry of the strain tensor Sij.
Juan Du, Fan Wu
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Weak solutions to stochastic porous media equations

open access: yes, 2004
Da Prato G, Röckner M. Weak solutions to stochastic porous media equations. Journal of Evolution Equations. 2004;4(2):249-271.A stochastic version of the porous medium equation is studied. The corresponding Kolmogorov equation is solved in a space L-2 (H,
Röckner, Michael, Da Prato, Giuseppe
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Equivalence of viscosity and weak solutions for the normalized p(x)-Laplacian

open access: yes, 2018
We show that viscosity solutions to the normalized p(x)-Laplace equation coincide with distributional weak solutions to the strong p(x)-Laplace equation when p is Lipschitz and inf p > 1. This yields C 1,α regularity for the viscosity solutions of
Siltakoski, Jarkko, Jarkko Siltakoski
core   +1 more source

WEAK SOLUTIONS FOR DISLOCATION TYPE EQUATIONS [PDF]

open access: yes, 2007
International audienceWe describe recent results obtained by G. Barles, P. Cardaliaguet, R. Monneau and the author recently. They are concerned with nonlocal Eikonal equations arising in the study of the dynamics of dislocation lines in crystals.
Ley, Olivier
core   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Regularity of weak solutions to the Landau-Lifshitz system in bounded regular domains

open access: yesElectronic Journal of Differential Equations, 2007
In this paper, we study the regularity, on the boundary, of weak solutions to the Landau-Lifshitz system in the framework of the micromagnetic model in the quasi-static approximation.
Kevin Santugini-Repiquet
doaj  

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