Results 81 to 90 of about 1,691,019 (337)

On the nonuniqueness of weak solution of the Euler equation [PDF]

Communications on Pure and Applied Mathematics, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

On asymptotic behavior of global solutions for hyperbolic hemivariational inequalities

Electronic Journal of Differential Equations, 2006
In this paper we study the existence of global weak solutions for a hyperbolic differential inclusion with a discontinuous and nonlinear multi-valued term. Also we investigate the asymptotic behavior of solutions.
Jong Yeoul Park, Sun Hye Park
doaj  

Space-dependent variable-order time-fractional wave equation: Existence and uniqueness of its weak solution

, 2022
Karel Van Bockstal, Ahmed S. Hendy, Mahmoud A. Zaky   +2 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Global weak solutions to the Navier-Stokes-Darcy-Boussinesq system for thermal convection in coupled free and porous media flows [PDF]

, 2021
Xiaoming Wang, Hao Wu
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Regularity for solutions to the Navier-Stokes equations with one velocity component regular

Electronic Journal of Differential Equations, 2002
In this paper, we establish a regularity criterion for solutions to the Navier-stokes equations, which is only related to one component of the velocity field. Let $(u, p)$ be a weak solution to the Navier-Stokes equations.
Cheng He
doaj  

Global compact attractors and complete bounded trajectories for compressible magnetohydrodynamic system of equations [PDF]

Theoretical and Applied Mechanics
In this article, we investigate the global behavior of magnetohydrodynamic (MHD) fluid’s weak solutions in three-dimensional bounded domain with a compact Lipschitz boundary driven by arbitrary forces.
Muhammad Jan
doaj   +1 more source