Results 11 to 20 of about 188,867 (310)

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Increasing weaning age of piglets from 4 to 7 weeks reduces stress, increases post-weaning feed intake but does not improve intestinal functionality [PDF]

, 2010
This study tested the hypothesis that late weaning and the availability of creep feed during the suckling period compared with early weaning, improves feed intake, decreases stress and improves the integrity of the intestinal tract.
Hoogendoorn, A., Dekker, R.A., Meulen, J., van der, Koopmans, S.J.   +3 more
core   +1 more source

Physiotherapy in critically ill patients

Revista Portuguesa de Pneumologia, 2011
Prolonged stay in Intensive Care Unit (ICU) can cause muscle weakness, physical deconditioning, recurrent symptoms, mood alterations and poor quality of life.Physiotherapy is probably the only treatment likely to increase in the short- and long-term care
N. Ambrosino, N. Janah, G. Vagheggini
doaj   +1 more source

Comparison of immediate withdrawal and stepwise reduction in duration of non-invasive ventilation in chronic obstructive pulmonary disease patients presenting with acute hypercapnic respiratory failure

Monaldi Archives for Chest Disease, 2023
There is no universally acceptable protocol for the withdrawal of non-invasive ventilation (NIV) in chronic obstructive pulmonary disease (COPD) patients presenting with acute hypercapnic respiratory failure (AHcRF).
Swetabh Purohit, Manu Madan, Rohit Kumar, Rajnish Kaushik, Pranav Ish, Mahendran AJ, Shibdas Chakrabarti, Neeraj Kumar Gupta, Nitesh Gupta   +8 more
doaj   +1 more source

Weaning Induces Stress-Dependent DNA Methylation and Transcriptional Changes in Piglet PBMCs

Frontiers in Genetics, 2021
Changes to the epigenome, including those to DNA methylation, have been proposed as mechanisms by which stress can induce long-term physiological changes in livestock species. Pig weaning is associated with dietary and social stress, both of which elicit
Ryan J. Corbett, Andrea M. Luttman, Kaitlin E. Wurtz, Janice M. Siegford, Nancy E. Raney, Laura M. Ford, Catherine W. Ernst   +6 more
doaj   +1 more source

Patient Characteristics and Outcomes of a Provincial Prolonged-Ventilation Weaning Centre: A Retrospective Cohort Study

Canadian Respiratory Journal, 2012
BACKGROUND: Growing numbers of critically ill patients require prolonged mechanical ventilation and experience difficulty with weaning. Specialized centres may facilitate weaning through focused interprofessional expertise with an emphasis on ...
Louise Rose, Ian M Fraser
doaj   +1 more source

Successful Co-Feeding of Asian Seabass, Lates calcarifer Larvae With Palm Oil-Based Microdiets and Live Feeds

Frontiers in Sustainable Food Systems, 2022
Palm oil has been recognized as a high potential alternative dietary lipid source to reduce the reliance on expensive fish oil in aquaculture feeds. Unfortunately, most research studies were focusing on the juvenile or grow-out stage of aquatic species ...
Nik Siti Zaimah Safiin, Fui Fui Ching, Rossita Shapawi   +2 more
doaj   +1 more source

Effect of pre-weaning concentrate supplementation on peripheral distribution of leukocytes, functional activity of neutrophils, acute phase protein and behavioural responses of abruptly weaned and housed beef calves [PDF]

, 2012
peer-reviewedBackground: The effect of pre-weaning concentrate supplementation on peripheral distribution of leukocytes, functional activity of neutrophils, acute phase protein response, metabolic and behavioural response, and performance of abruptly ...
Lynch Eilish M, McGee, Mark, Lynch, Eilish M, McGee Mark, Mark McGee, Lynch, Eilish M., Earley Bernadette, Bernadette Earley, Doyle, Sean, Doyle Sean, Sean Doyle, Earley, Bernadette, Eilish M Lynch   +12 more
core   +1 more source

Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology [PDF]

, 2012
peer-reviewedBackground: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal ...
David J Lynn, Lynn David J, McGee, Mark, O'Loughlin, Aran, Lynn, David J, McGee Mark, Matthew McCabe, McCabe, Matthew, O’Loughlin, Aran, Mark McGee, O’Loughlin Aran, Earley Bernadette, McCabe Matthew, Bernadette Earley, Doyle, Sean, Doyle Sean, Aran O’Loughlin, Sean Doyle, Earley, Bernadette, Lynn, David J.   +19 more
core   +1 more source

Unexpected death of a ventilator-dependent amyotrophic lateral sclerosis patient

Revista Portuguesa de Pneumologia, 2013
Background: Amyotrophic lateral sclerosis (ALS) is a fatal, progressive, neurodegenerative disease and most patients affected die of respiratory compromise and/or pneumonia within 2–3 years of diagnosis.
M. di Paolo, L. Evangelisti, N. Ambrosino   +2 more
doaj   +1 more source