Results 201 to 210 of about 278,985 (286)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

open access: yesResponsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma   +8 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo   +10 more
wiley   +1 more source

Arkansas Animal Science Department Report 2015 [PDF]

open access: yes, 2015
Apple, Jason   +3 more
core   +2 more sources

Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions

open access: yesVeterinary Record, EarlyView.
Abstract Background In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri‐ and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical ...
Axel Sannö   +3 more
wiley   +1 more source

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