Results 41 to 50 of about 346,026 (340)
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Chinese Journal of Mechanical Engineering, 2023 Titanium alloy has been applied in the field of aerospace manufacturing for its high specific strength and hardness. Nonetheless, these properties also cause general problems in the machining, such as processing inefficiency, serious wear, poor workpiece
Tao Chen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
Evolution of Fretting Wear Behaviors and Mechanisms of 20CrMnTi Steel after Carburizing
Metals, 2020 In this paper, the fretting wear properties of 20CrMnTi steel, a common material for a rocker bracket, was discussed for the first time after it was suffered carburizing treatment.
Jinchi Tang +7 more
doaj +1 more source
, 2023 Wear - is a change in the size, shape, mass or condition of the surface of a product or structure due to destruction (wear) of the surface layer. Abrasive wear is the destruction of the surface by hard abrasive grains. There are two possible types of impact of abrasive grains on the surface.
openaire +2 more sources
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Friction, 2023 The polyetheretherketone (PEEK)-highly cross-linked polyethylene (XLPE), all-polymer knee prosthesis has excellent prospects for replacing the traditional metal/ceramic-polyethylene joint prosthesis, improving the service life of the joint prosthesis and
Xinyue Zhang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
A frictional contact problem with wear diffusion [PDF]
, 2019 This paper constructs and analyzes a model for the dynamic frictional contact between a viscoelastic body and a moving foundation. The contact involves wear of the contacting surface and the diffusion of the wear debris. The relationships between the stresses and displacements on the contact boundary are modeled by the normal compliance law and a ...
arxiv +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source