Results 41 to 50 of about 2,260,252 (243)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Towards a Convergent Development of Learning Analytics [PDF]

, 2017
In the last 7 years, since the first LAK conference, Learning Analytics has grown rapidly as a field from a small group of interested scholars and practitioners to one of the most scientifically successful and institutionally accepted areas of Learning ...
Hershkovitz, A, Wise, A, Ochoa, X, Alyssa Wise, Xavier Ochoa, Arnon Hershkovitz, Knight, S, Simon Knight   +7 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Towards cloud based big data analytics for smart future cities [PDF]

, 2015
A large amount of land-use, environment, socio-economic, energy and transport data is generated in cities. An integrated perspective of managing and analysing such big data can answer a number of science, policy, planning, governance and business ...
Anjum, Ashiq, Soomro, Kamran, Tahir, Muhammad, Khan, Zaheer, Tahir, Muhammad Atif, Soomro, Kamran Ahmed   +5 more
core   +1 more source

How Much is Much?: a Conceptual Study of Web Traffic

Liber Quarterly: The Journal of European Research Libraries, 2012
Valid and relevant statistics are required for library planning and advocacy. As libraries and their users turn to the web, library statistics must follow.
Tord Høivik
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

What Makes Learning Analytics Research Matter [PDF]

, 2021
The ongoing changes and challenges brought on by the COVID-19 pandemic have exacerbated long-standing inequities in education, leading many to question basic assumptions about how learning can best benefit all students.
Wise, AF, Ochoa, X, Knight, S
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The Contribution of Digital Technology to the Forecasting of Supply Chain Development, in IT Products, Modeling and Simulation of the Problem

Forecasting, 2022
Aiming for the forecasting and predictability of their future development, corporations have developed appropriate strategies as a result of the necessity to optimize the distribution networks of new IT products over time.
Dimitrios K. Nasiopoulos, Dimitrios M. Mastrakoulis, Dimitrios A. Arvanitidis   +2 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source