Results 51 to 60 of about 2,260,252 (243)

Time for Change: Why Learning Analytics Needs Temporal Analysis [PDF]

open access: yes, 2017
Learning is a process that occurs over time: We build understanding, change perspectives, and develop skills over the course of extended experiences. As a field, learning analytics aims to generate understanding of, and support for, such processes of ...
Bodong Chen   +5 more
core   +1 more source

Research of the marketing instruments of adoption of management decisions in the field of planning and business development

open access: yesВестник университета, 2019
The analysis of the elements, included in the digital marketing complex, has been сonducted. One of the most popular marketing tools – digital funnel of sales has been considered.
A. S. Zinchenko, V. A. Kolosova
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

On web-applications usability testing

open access: yesРоссийский технологический журнал, 2020
The paper discusses the task of organizing the usability testing of web applications that are in pilot or industrial operation. A usability testing technique is described that combines the development, debugging and execution of test scenarios, and ...
Boris M. Basok   +2 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Training of Specialists in the Field of Electronic Marketing: Staff for the Digital Economy of the Republic of Belarus

open access: yesЦифровая трансформация, 2017
The tendencies of development of marketing in conditions of digital transformation of economy are considered in the article. The concept of electronic marketing is presented.
L. I. Arhipova   +4 more
doaj   +2 more sources

Trends in access of plant biodiversity data revealed by Google Analytics

open access: yesBiodiversity Data Journal, 2014
The amount of plant biodiversity data available via the web has exploded in the last decade, but making these data available requires a considerable investment of time and work, both vital considerations for organizations and institutions looking to ...
Timothy Jones   +7 more
doaj   +1 more source

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