Results 171 to 180 of about 525,186 (281)

Young People's Satisfaction With and Perceived Impact of a Multichannel Mental Health Helpline During and After COVID-19 Pandemic: Mixed Methods Analysis of Cross-Sectional Survey Data. [PDF]

JMIR Form Res
Phua SW, Jan A, Zheng G, Gutman LM.
europepmc   +1 more source

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Software and pipelines for registration and analyses of rodent brain image data in reference atlas space. [PDF]

Front Neuroinform
Puchades MA, Yates SC, Csucs G, Carey H, Balkir A, Leergaard TB, Bjaalie JG.   +6 more
europepmc   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Integrated Network Solutions in Government Hiring Trends (INSIGHT+). [PDF]

Sci Data
Resh WG, Lee KE, Ming Y, Xia XA, Dias N, Liu KA, Cao D, Huh W.   +7 more
europepmc   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

Labelled IoT flow-based network traffic dataset for cyberattack detection. [PDF]

Data Brief
Martínez B, Cambra C, Urda D, Rincón J, Herrero Á.   +4 more
europepmc   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

The ocean's biological carbon pump under pressure. [PDF]

Sci Adv
Middelburg JJ.
europepmc   +1 more source

Show Me the Brain!!: A modern approach to neuroanatomy education

Anatomical Sciences Education, EarlyView.
Abstract Show Me the Brain!! (SMtB) is a digital system for interactive graphics that is designed to support instruction in neuroanatomy and neuroscience. It will soon be made open‐source and freely available. SMtB bridges medical and traditional neuroanatomy instruction with the computational systems and representational conventions common in ...
Nicholas C. Hindy, Anthony J. Bishara, Ellie Lovellette, John R. Pani   +3 more
wiley   +1 more source