Results 161 to 170 of about 269,724 (274)

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Exploring the digital landscape: A scoping review of Achilles tendinopathy education on public websites and in randomised controlled trials. [PDF]

Clin Rehabil
Malliaras P, Mallows A, McAullife S, Chimenti RL, Chen W, Deng J, Jiang J, Sharma S, Potter M, Smitheman H, Sancho I, Tavakkoli Oskouei S, Nicklen P, Bourke J, Fleagle T, Ruffino D, Silbernagel K, de Vos RJ.   +17 more
europepmc   +1 more source

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

Advanced Science, EarlyView.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang, Bohao Liu, Xingzhuo Zhu, Deqian Qiao, Sizhe Chen, Xiaoyan Zeng, Qingqing Yang, Zihuan Wei, Yinjuan Huang, Jizhao Wang, Guangjian Zhang, Qiuyu Gong   +11 more
wiley   +1 more source

Online Questions About Clubfoot Surgery: Content Analysis and Development of a Patient Education Resource. [PDF]

J Pediatr Soc North Am
Vicioso C, Javier J, Huang JJ, Torres RB, Balachandran U, Nietsch K, Locke AR, Koehne NH, Ren R, Tully N, Ranade SC.   +10 more
europepmc   +1 more source

Small Language Models for Phishing Website Detection: Cost, Performance, and Privacy Trade-Offs

Goldenits, Georg, Koenig, Philip, Raubitzek, Sebastian, Ekelhart, Andreas   +3 more
openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Development of an Information System for Monitoring, Data Collection and Reporting of Turtle Conservation in the Essential Ecosystem Area (KEE) of Kili Kili Beach, Trenggalek Regency, Based on the Website

Muhammad Derry Ramadhan, Vian Dedi Pratama   +1 more
openalex   +2 more sources

Waspadai Penerobosan Publisitas Lotere Online Di Website Negeri

, 2023
edhelmzkes
openalex   +2 more sources

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

Advanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang, Huanyu Wang, Qianqian Kang, Ruping Pan, Rui He, Min Yang, Jiadai Liu, Xuemin Peng, Yuyu Xie, Hongyan Deng, Wenshe Wang, Zengzhe Zhu, Jing Ge, Yulian Liu, Ronghui Gao, Yaming Guo, Peng Yu, Limeng Pan, Danpei Li, Pema Maretich, Xiaoping Luo, Xuefeng Yu, Yong Chen   +22 more
wiley   +1 more source

Website: Set up website

Network website online (6)
openaire   +1 more source