Abstract INTRODUCTION Genome‐wide association studies (GWAS) have identified 80+ genetic loci associated with Alzheimer's disease (AD), enabling the development of polygenic risk scores (PRS). However, the predictive accuracy of PRS in diverse populations remains low.
Meri Okorie +9 more
wiley +1 more source
Assessing Executive Functions in Children With Developmental Dyslexia: A Comprehensive Approach. [PDF]
Guerra A +11 more
europepmc +1 more source
Abstract INTRODUCTION Dementia clinical risk scores (CRSs) provide accessible tools for identifying individuals at risk for Alzheimer's disease (AD) and related dementias, yet their performance across diverse populations and relationships to AD endophenotypes remains unclear.
Meri Okorie +5 more
wiley +1 more source
CSF fibrinogen predicts longitudinal Tau accumulation in cognitively unimpaired older adults
Abstract INTRODUCTION Blood–brain barrier (BBB) dysfunction is an early feature of Alzheimer's disease (AD). Fibrinogen represents a sensitive marker of BBB leakage, but whether it modifies longitudinal tau progression in cognitively unimpaired (CU) individuals remains unknown.
Christos Panagiotis Lisgaras +21 more
wiley +1 more source
Beyond reading and spelling: exploring intelligence profiles in individuals with dyslexia through a Cattell-Horn-Carroll theory lens. [PDF]
Radtke BM +4 more
europepmc +1 more source
Abstract INTRODUCTION Visit‐to‐visit blood pressure variability (BPV) may be associated with cognitive decline beyond mean blood pressure (BP), but its relevance across treatment contexts remains uncertain. METHODS We pooled individual‐participant data from Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes (ACCORD‐MIND) and Systolic ...
Yue Qiao +4 more
wiley +1 more source
What Lies Behind Diagnostic Labels? High Intra-Individual Variability Is the True Cognitive Signature of University Students with Specific Learning Disorders. [PDF]
Zonca S, Bizzaro ML, Girelli L.
europepmc +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
ToM<sup>2</sup> : Parental Perception of Theory of Mind Abilities in Autistic Children. [PDF]
Joseph LS, Perez M, Perry A, Koller J.
europepmc +1 more source
The Unique Roles of Executive Function in Co‐Occurring Psychopathologies in Autism
ABSTRACT Children with autism spectrum disorder (ASD) often experience co‐occurring psychiatric conditions, such as anxiety and attention‐deficit/hyperactivity disorder (ADHD), which significantly impair daily functioning. However, the underlying mechanisms linking these conditions to core ASD features remain poorly understood.
Shing‐Him Ng +13 more
wiley +1 more source

