Results 71 to 80 of about 1,979 (216)
IEEE AccessThis study investigates the impact of corona discharge plasma treatments on the phytochemical composition, antioxidant activity, and neuroprotective potential of Eclipta prostrata Linn. (Kameng) grown from plasma-treated seeds.
Weerasak Samee +6 more
doaj +1 more source
Journal of Natural Remedies, 2023 Drug resistance and poor therapeutic outcomes are the emerging problems pertaining to cisplatin treatment in ovarian cancer. The effectiveness of the conventional chemotherapeutic medication could be improved by combining with natural drugs.
Gloria Jemmi Christobel Robinson +3 more
semanticscholar +1 more source
Potential of Cogon Grass as an Oil Sorbent [PDF]
, 2012 Experiments on the potential of Cogon grass (lmperata cylindrica), a weed harmful to other plants, for use as a low-cost and biodegradable oil sorbent were carried out under various spill conditions.
Anggraini, I. F. (Irni) +3 more
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Inflammatory responses in epithelia: endotoxin-induced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells [PDF]
, 2010 Background IL-6 is a pro-inflammatory cytokine that signals via binding to a soluble or membrane bound receptor, while nitric oxide (NO), an oxidative stress molecule, diffuses through the cell membrane without a receptor.
Maalouf, Samar W +2 more
core +3 more sources
Drug Design, Development and Therapy, 2020 Sadia Sarwar,1,2 Jun Qing Yu,1 Humaira Nadeem,3 Fazlul Huq1 1Discipline of Biomedical Sciences, Sydney Medical School, The University of Sydney, Cumberland Campus, Sydney, NSW, Australia; 2Department of Pharmacognosy, Riphah Institute of Pharmaceutical ...
Sarwar S, Yu JQ, Nadeem H, Huq F
doaj
Hypolipemic, hepatoprotective effect and the related mechanism of wedelolactone [PDF]
, 2015 目的：蟛蜞菊内酯属于呋喃香豆素类，据文献报道其具有抑制肝细胞纤维化、抗炎、 免疫调节、抗绝经后骨质疏松等作用，本文首次探讨蟛蜞菊内酯的降血脂作用及相关机 制。方法：首先通过体外实验观察蟛蜞菊内酯对脂质代谢相关基因和蛋白表达的影响。 HepG2细胞给药24h，提取蛋白及RNA，采用蛋白印迹法测定腺苷酸活化蛋白激酶 (AMPK)和过氧化物酶体增殖物活化受体α（PPARα）的蛋白表达水平，用实时荧光定量 PCR方法检测AMPK、PPARα、低密度脂蛋白受体（LDLR）以及脂蛋白脂酶(LPL)基因 表达水平 ...
彭璐
core
Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression [PDF]
, 2011 Background Previous studies showed that mesothelin (MSLN) plays important roles in survival of pancreatic cancer (PC) cells under anchorage dependent/independent conditions as well as resistance to chemotherapy.
Bharadwaj, Uddalak +4 more
core +3 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
MedComm, Volume 6, Issue 11, November 2025.Ligand–receptor binding activates PLC, which hydrolyzes the membrane lipid PIP2, generating the second messenger's IP3 and DAG. IP3 binding to ER receptors causes Ca2⁺ release. Subsequently, PKC are recruited to the membrane, which induces a conformational change in PKC, leading to the full enzymatic activation.
Yongqi Li +8 more
wiley +1 more source
NFkB Disrupts Tissue Polarity in 3D by Preventing Integration of Microenvironmental Signals [PDF]
, 2013 The microenvironment of cells controls their phenotype, and thereby the architecture of the emerging multicellular structure or tissue. We have reported more than a dozen microenvironmental factors whose signaling must be integrated in order to effect an
Akavia, Uri-David +8 more
core +3 more sources