Noncanonical inflammasomes: caspase-11 activation and effector mechanisms.
Inflammasomes are cytosolic, multiprotein complexes assembled by members of the NOD-like receptor (NLR) and PYHIN protein families in response to pathogen-associated molecular patterns (PAMPs) and danger signals, and serve as activation platforms for caspase-1.
Petr Broz, Denise M Monack
doaj +7 more sources
Esketamine mitigates endotoxin-induced acute lung injury by suppressing caspase-11-driven pyroptosis. [PDF]
Bao Y +6 more
europepmc +1 more source
Disulfiram ameliorates ischemia/reperfusion-induced acute kidney injury by suppressing the caspase-11-GSDMD pathway. [PDF]
Cai Q +7 more
europepmc +1 more source
Caspase-11 regulates systemic inflammation and cell death in a cell-specific manner after trauma with shock. [PDF]
Mulla J +7 more
europepmc +1 more source
Curcumin inhibits cerebral ischaemia-reperfusion injury and cell apoptosis in rats through the ERK-CHOP-caspase-11 pathway. [PDF]
Chen Y, Zhang L, Yang Z, Yu J.
europepmc +1 more source
Regulatory Roles of Caspase-11 Non-Canonical Inflammasome in Inflammatory Liver Diseases. [PDF]
Yi YS.
europepmc +1 more source
Korean Red Ginseng Saponins Play an Anti-Inflammatory Role by Targeting Caspase-11 Non-Canonical Inflammasome in Macrophages. [PDF]
Cho HJ, Kim E, Yi YS.
europepmc +1 more source
ZAKα Induces Pyroptosis of Colonic Epithelium Via the Caspase-11/GSDMD Pathway to Aggravate Colitis. [PDF]
Li S +11 more
europepmc +1 more source
The Protective Effects of Goitrin on LPS-Induced Septic Shock in C57BL/6J Mice via Caspase-11 Non-Canonical Inflammasome Inhibition. [PDF]
Ruan D +7 more
europepmc +1 more source
Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11. [PDF]
Harberts EM +5 more
europepmc +1 more source

