Results 61 to 70 of about 3,063 (203)

CTSC Confers Radioresistance in Hepatocellular Carcinoma by Regulating Myeloid‐Derived Suppressor Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Radiotherapy is an important therapeutic modality for advanced hepatocellular carcinoma (HCC), but the limited understanding of radioresistance mechanisms in HCC has hindered its further clinical development. This work aimed to clarify the essential role of Cathepsin C (CTSC) in regulating radioresistance in HCC.
Jiahuan Xu, Bilin Zhang, Shirui Yang, Shaoran Song, Jie Wu, Yunzhi Dang   +5 more
wiley   +1 more source

Pseudotumor pulmonar como apresentação inicial de granulomatose de Wegener Lung pseudotumor as the initial presentation of Wegener's granulomatosis

Jornal Brasileiro de Pneumologia, 2009
A granulomatose de Wegener é uma doença inflamatória multissistêmica de etiologia desconhecida, que se caracteriza por vasculite de pequeno e médio calibre. As manifestações clínicas mais comuns envolvem o trato respiratório superior, pulmões e rins e as
Marcelo Fouad Rabahi, Ludmila Bertti Coelho, Eliza de Oliveira Borges, Marcella Stival Lemes, Weniskley Mendes de Castro, Siderley de Souza Carneiro   +5 more
doaj   +1 more source

Therapeutic Dilemmas in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Diffuse Alveolar Hemorrhage and Venous Thromboembolism

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Diffuse alveolar hemorrhage (DAH) is a life‐threatening presentation of antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Patients with AAV are at an increased risk of venous thromboembolic events (VTEs). These manifestations can co‐occur; however, the prognosis and management of these patients are poorly understood. Methods In
Elif D. Ediboglu, Samuel D. Falde, Misbah Baqir, Rodrigo Cartin‐Ceba, Robert McBane, Ulrich Specks   +5 more
wiley   +1 more source

Granulomatose de Wegener – Forma limitada

Revista Portuguesa de Pneumologia, 2002
RESUMO: Doente do sexo feminino, 53 anos de idade, internada por lesões nodulares pulmonares sugestivas de doença metastática.Antecedentes de Doença de Graves e de Pyoderma gangrenosum.Biópsia pulmonar compatível com Granulomatose de Wegener.REV ...
I. Gil, J. Porto, B. Fernandes, M. Gonçalo, L. Carvalho, J.D. Vieira, J.J. Moura   +6 more
doaj   +1 more source

Safety of Immune Checkpoint Inhibitors in Cancer Patients With Preexisting Autoimmune Vasculitis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Immune checkpoint inhibitors (ICIs) are effective cancer therapies but often cause serious immune‐related adverse events (irAEs). Patients with preexisting autoimmune diseases, including vasculitis, are excluded from trials. We aimed to evaluate the frequency, severity, and outcomes of vasculitis flares and irAEs in this population.
Juan Sevillano, Noha Abdel‐Wahab, Yixuan Zhou, Juan I. Ruiz, Maria E. Suarez‐Almazor   +4 more
wiley   +1 more source

Granulomatosis With Polyangiitis Presenting as Deep Vein Thrombosis in an Adolescent: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Granulomatosis with polyangiitis can rarely present as deep vein thrombosis in adolescents. Unexplained thrombosis in a young patient, accompanied by systemic inflammatory features, should raise suspicion for an underlying vasculitis. Early recognition and prompt initiation of immunosuppressive therapy alongside anticoagulation are crucial to ...
Bishal Budha, Aron Shrestha, Satish Bajracharya, Dhiraj Poudel, Bishweshar Joshi, Pujan Pandey, Rajan Budha, Sadikshya Pandey, Bishal Panthi   +8 more
wiley   +1 more source

Livedo retikularis pada penderita Granulomatosis Wegener SUATU LAPORAN KASUS.

, 1996
Elly Moedijatmini, Bambang Setyo, Fadjar Waskito â Livedo reticularis in a patients with Wegener Granulomatosis. A case report. Livedo reticularis (LR) is a skin lesion which is characterized by a reddish blue mottling in a fishnet reticular pattern ...
Elly Moedijatmini, Bambang Setyo, dan Fadjar Waskito
core   +1 more source

Diagnostic Consideration for Sinonasal Wegener’s Granulomatosis Clinically Mistaken for Carcinoma

Case Reports in Otolaryngology, 2013
We report a case of Wegener’s granulomatosis clinically mistaken for carcinoma in a 21-year-old girl presenting with an ulcerated mass of the nasopharynx associated with enlarged laterocervical nodes.
Cristina La Rosa, Carmela Emmanuele, Maria Grazia Tranchina, Massimo Ippolito, Sebastiano Cosentino, Vincenzo Saita, Giuseppina Improta, Filippo Fraggetta   +7 more
doaj   +1 more source

Wegner′s granulomatosis developing for the first time in a patient eight years after starting maintenance hemodialysis

Saudi Journal of Kidney Diseases and Transplantation, 2015
Wegener′s granulomatosis is a serious autoimmune disorder characterized by necrotizing small-vessel vasculitis. It is a multisystem disease that primarily affects the lung and kidneys.
Ahmad Ramadan Ali, Kamel El-Reshaid
doaj   +1 more source

A Rare Case of Conjunctival and Scleral Necrosis Following Anterior Sub‐Tenon Triamcinolone Acetonide Injection in a Pediatric Patient

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT The sub‐Tenon route for injecting triamcinolone acetonide is one of the widely practiced surgical techniques for postoperative inflammation control, but complicated conjunctival and scleral necrosis are rare occurrences. A 3‐year‐old boy underwent bilateral cataract surgery and an anterior sub‐tendon injection of triamcinolone (AST) (20 mg ...
Muhammad Mateen Amir, Minahal Mateen, Bilal Aslam, Shafiq Ur Rahman, Fazeela Bibi, Khalil El Abdi, Said Hamid Sadat   +6 more
wiley   +1 more source