Results 61 to 70 of about 5,850 (214)

Vasculitides associated with IgG antineutrophil cytoplasmic autoantibodies in childhood [PDF]

, 2018
Immunoglobulin (Ig)G antineutrophil cytoplasmic autoantibodies are causally associated with necrotizing vasculitides that are characterized immunopathologically by little or no deposition of immunoreactants, such as Wegener granulomatosis, microscopic ...
Bettinelli, Alberto, Bianchetti, Mario, Keller, Franco, Simonetti, Giacomo, Vanoni, Federica   +4 more
core  

CTSC Confers Radioresistance in Hepatocellular Carcinoma by Regulating Myeloid‐Derived Suppressor Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Radiotherapy is an important therapeutic modality for advanced hepatocellular carcinoma (HCC), but the limited understanding of radioresistance mechanisms in HCC has hindered its further clinical development. This work aimed to clarify the essential role of Cathepsin C (CTSC) in regulating radioresistance in HCC.
Jiahuan Xu, Bilin Zhang, Shirui Yang, Shaoran Song, Jie Wu, Yunzhi Dang   +5 more
wiley   +1 more source

Frozen Eye in Granulomatosis with Polyangiitis (Wegener's)

Proceedings of Singapore Healthcare, 2013
Ocular involvement in Granulomatosis with Polyangiitis (GP or Wegener Granulomatosis) is a potentially serious disease manifestation which needs prompt diagnosis and treatment.
Qin Yan MRCP, Audrey Lee Geok Looi FRCS, Julian Thumboo FRCP   +2 more
doaj   +1 more source

Compromiso renal en un paciente con granulomatosis de Wegener: caso clínico y revisión de la literatura

Revista Colombiana de Nefrología, 2017
El presente manuscrito se hace con el fin de reportar un caso del tema en mención y realizar una revisión de la literatura disponible más reciente con respecto al diagnóstico y tratamiento. Antecedentes La granulomatosis de Wegener (GW) se caracteriza
José Luis Fabris Vargas, Gilberto Jaramillo, Rodolfo Torres, Carlos Rosselli, Orlando Olivares   +4 more
doaj   +1 more source

Granulomatosis With Polyangiitis in Otolaryngologist Practice: A Review of Current Knowledge [PDF]

Clinical and Experimental Otorhinolaryngology, 2016
Granulomatosis with polyangiitis (GPA) is an idiopathic vasculitis of medium and small arteries, characterized by necrotizing granulomatous inflammation. GPA typically affects upper and lower respiratory tract with coexisting glomerulonephritis.
Joanna Wojciechowska, Wojciech Krajewski, Piotr Krajewski, Tomasz Kręcicki   +3 more
doaj   +1 more source

Types of Angiopathy in Experimental Autoimmune Disease in Rats [PDF]

, 2017
The purpose and objectives of this work were to study the nature of the heart, lungs and kidneys angiopathy in rats with a model of systemic autoimmune disease, carrying out comparisons of the results with extravasal morphological manifestations of the ...
Iegudina, Y. (Yelizaveta), Mikuksts, V. (Viktoriya), Syniachenko, O. (Oleg), Yakovlenko, P. (Pavel)   +3 more
core   +2 more sources

Therapeutic Dilemmas in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Diffuse Alveolar Hemorrhage and Venous Thromboembolism

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Diffuse alveolar hemorrhage (DAH) is a life‐threatening presentation of antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Patients with AAV are at an increased risk of venous thromboembolic events (VTEs). These manifestations can co‐occur; however, the prognosis and management of these patients are poorly understood. Methods In
Elif D. Ediboglu, Samuel D. Falde, Misbah Baqir, Rodrigo Cartin‐Ceba, Robert McBane, Ulrich Specks   +5 more
wiley   +1 more source

Wegener´s granulomatosis in a young patient preceded by localized cutaneous manifestations

Dermatology Reports, 2011
Wegener´s granulomatosis (WG) is a rare, systemic vasculitis involving multiple organs. The clinical presentation is highly diverse, and there is considerable risk of mortality if diagnosis and treatment are delayed.
Jesper Smit, Jakob Lykke Poulsen, Jakob Sølling, Carsten Sauer Mikkelsen   +3 more
doaj   +1 more source

Granulomatosis with Polyangiitis (Wegener's): An alternative name for Wegener's Granulomatosis [PDF]

Arthritis & Rheumatism, 2011
The Boards of Directors of the American College of Rheumatology, the American Society of Nephrology, and the European League Against Rheumatism recommend a gradual shift from honorific eponyms to disease-descriptive or etiology-based nomenclature.
Falk, R. J., Gross, W. L., Guillevin, L., Hoffman, G., Jayne, D. R. W., Jennette, J. C., Kallenberg, C. G. M., Luqmani, R., Mahr, A. D., Matteson, E. L., Merkel, P. A., Specks, U., Watts, R.   +12 more
openaire   +9 more sources

Safety of Immune Checkpoint Inhibitors in Cancer Patients With Preexisting Autoimmune Vasculitis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Immune checkpoint inhibitors (ICIs) are effective cancer therapies but often cause serious immune‐related adverse events (irAEs). Patients with preexisting autoimmune diseases, including vasculitis, are excluded from trials. We aimed to evaluate the frequency, severity, and outcomes of vasculitis flares and irAEs in this population.
Juan Sevillano, Noha Abdel‐Wahab, Yixuan Zhou, Juan I. Ruiz, Maria E. Suarez‐Almazor   +4 more
wiley   +1 more source