The Drug Safety Framework of Avacopan: A Pharmacovigilance Study
We identified 11 previously unreported potential adverse events associated with avacopan. No high‐priority clinical events were observed; however, special attention should be paid to the potential possibility of avacopan‐induced vanishing bile duct syndrome (Logos and icons displayed in the sections “Safety Framework” and “Data Sources and ...
Tianqi Chang +4 more
wiley +1 more source
Granulomatose de Wegener Wegener's granulomatosis
A granulomatose de Wegener caracteriza-se por vasculite necrosante granulomatosa que acomete preferencialmente vias aéreas superiores, inferiores e rins.
Telma Antunes +1 more
doaj +1 more source
Chemosensory function in Wegener's granulomatosis: a preliminary report [PDF]
Despite the fact that Wegener's granulomatosis affects the nasal and paranasal cavities and the cranial nerves regularly, chemosensory impairments have not been reported.
Cao Van, Helene +4 more
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Clinical and Pathological Features of Vasculitic Neuropathy: A Single‐Center Study in China
Vasculitic neuropathy in mainland China predominantly presents as axonal sensorimotor neuropathy. Systemic VN shows more frequent transmural inflammatory infiltration, whereas EGPA is more common in cases without infiltration. Most treated patients achieved remission, and the overall prognosis was relatively favorable, underscoring the importance of ...
Xiaoyu Zhou +9 more
wiley +1 more source
Wegener′s granulomatosis is a serious autoimmune disorder characterized by necrotizing small-vessel vasculitis. It is a multisystem disease that primarily affects the lung and kidneys.
Ahmad Ramadan Ali, Kamel El-Reshaid
doaj +1 more source
PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2 [PDF]
Background Anti-neutrophil cytoplasmic antibodies (ANCA) is autoantibodies characteristic of vasculitis diseases. A connection between ANCA and Wegener's granulomatosis was well established. The interaction of both ANCA phenotypes (PR3-ANCA and MPO-ANCA)
Iwashiro Atsushi +3 more
core +2 more sources
Currently, the animals commonly used to establish animal models of benign airway stenosis (BAS) include mice, rats, pigs, dogs, rabbits, and ferrets. The establishment methods involve one or a combination of two methods such as mechanical injury, tracheal cautery, cuff overpressure intubation, laser injury, and endoscopic silver nitrate cauterization ...
Wusheng Zhang +6 more
wiley +1 more source
Diagnostic Consideration for Sinonasal Wegener’s Granulomatosis Clinically Mistaken for Carcinoma
We report a case of Wegener’s granulomatosis clinically mistaken for carcinoma in a 21-year-old girl presenting with an ulcerated mass of the nasopharynx associated with enlarged laterocervical nodes.
Cristina La Rosa +7 more
doaj +1 more source
Wegener′s granulomatosis of urinary tract presenting as bladder outlet obstruction
We report a rare case of Wegener′s granulomatosis involving the prostate gland in a 45-year-old male who presented with acute urinary retention. Treatment was initiated with oral cyclophosphamide and steroids.
V Suryaprakash +5 more
doaj +1 more source
A Wegener granulomatózis és a gyulladásos miopátiák tüdőmanifesztációjának klinikai megjelenésével és ezek kialakulásához vezető immunológiai eltérésekkel kapcsolatos vizsgálatok [PDF]
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Komócsi András
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