Results 151 to 160 of about 6,786,852 (260)

Differential Sperm DNA Methylation Profiles in Healthy Men With High Versus Low Adherence to the Mediterranean Diet in the Led‐Fertyl Study

Andrology, EarlyView.
ABSTRACT Background Diet is known to play an essential role not only in sperm quality but also in offspring health, likely mediated through the sperm epigenome. Moreover, one of the main components of the Mediterranean diet (MedDiet) (i.e., nuts) have shown to impact sperm DNA methylation patterns.
Rashmi Agarwal, Nancy Babio, Estefanía Davila‐Cordova, María Fernández de la Puente, Cristina Valle‐Hita, Carles Arribas, Manel Esteller, Aleix Noguera‐Castells, Raquel Pluvinet, Jordi Salas‐Salvadó, Albert Salas‐Huetos   +10 more
wiley   +1 more source

Hypogonadism in Cisgender Men Living With HIV: Prevalence, Clinical and Metabolic Features

Andrology, EarlyView.
ABSTRACT Background Hypogonadism is frequently observed in men living with human immunodeficiency virus (HIV), although its prevalence, etiology, and predictors remain incompletely understood. Objective To evaluate the prevalence of hypogonadism and its association with metabolic factors in men living with HIV (MLWH), on stable antiretroviral therapy ...
Felipe Augusto Azevedo Leao, Gabriel Cabreira Nunes, Manuela Almeida Ribeiro, Luiza Costa da Fonseca, Aline Cristina Miranda Marinho Costa, Mateus Rodrigues Westin, Unai Tupinambas, Milena Maria Moreira Guimaraes, Leticia Ferreira Gontijo Silveira   +8 more
wiley   +1 more source

Lower Systolic Blood Pressure in 67 Boys With Klinefelter Syndrome Compared to 1842 Healthy Danish Boys

Andrology, EarlyView.
ABSTRACT Objective Our objective was to develop age‐ and height‐specific reference ranges for blood pressure, pulse pressure and mean arterial pressure in healthy boys and to compare these to measurements in patients with Klinefelter syndrome followed longitudinally through childhood and adolescence. Design Cohort study consisting of a population‐based
Andrés Felipe Ø. Fritzbøger, Riccardo Battiston, Cecilie N. Larsen, Anna Sophie L. Kjaer, Klaus Juul, Ida M. Schmidt, Jørgen H. Petersen, Katharina M. Main, Anders Juul, Lise Aksglaede   +9 more
wiley   +1 more source

All‐cause mortality after self‐reported vs. hospital‐reported gynecological surgery: The HUNT study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Mortality risk after hysterectomy and oophorectomy varied between hospital‐reported and self‐reported exposure. This could explain the heterogeneity between previous studies. In this study, hospital‐reported hysterectomy and bilateral oophorectomy were not associated with increased mortality risk, but early bilateral oophorectomy was.
Tina Ellinor Rosland, Nora Johansen, Astrid Helene Liavaag, Bjørn Olav Åsvold, Are Hugo Pripp, Trond Melbye Michelsen   +5 more
wiley   +1 more source

Review Article: Fibrosis‐4 Index in Steatotic Liver Disease—Past, Present and Future

Alimentary Pharmacology &Therapeutics, EarlyView.
FIB‐4 remains an inexpensive, scalable first‐line triage tool for excluding advanced fibrosis and identifying patients who need second‐line assessment, but it should not be used as a stand‐alone diagnostic or treatment‐selection test. Sequential testing and longitudinal FIB‐4 trajectories may improve risk stratification and prognosis.
Kriti Soni, Vinay Jahagirdar, Omar Albhaisi, Richard K. Sterling, Juan Pablo Arab, Hanna Blaney, Luis Antonio Díaz   +6 more
wiley   +1 more source

The ongoing oleoylethanolamide story: Therapeutic implications in the control of obesity and its comorbidities

British Journal of Pharmacology, EarlyView.
The global burden of obesity continues to rise, demanding effective pharmacological strategies for individuals in whom prevention alone is insufficient. Recent incretin‐based and multi‐agonist therapies have delivered unprecedented weight loss, demonstrating that the simultaneous modulation of multiple metabolic pathways can optimize body weight ...
Marzia Friuli, Alessia Campagna, Barbara Eramo, Christian Sepe, Annarita Zuena, Silvana Gaetani, Adele Romano   +6 more
wiley   +1 more source

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton, Elham Kamran, Lehana Thabane, Peter Yin, Rebecca Christensen   +4 more
wiley   +1 more source

Association between weight-adjusted-waist index and periodontitis risk: A cross-sectional study.

BackgroundThere may be an association between obesity and periodontitis, yet no studies have investigated the correlation between the new obesity indicator, the weight-adjusted-waist Index (WWI), and periodontitis.ObjectiveThis study aims to investigate ...
Xinyu Wu
core   +1 more source

Weight Regain After Incretin Treatment: The Lean Mass Deficit Hypothesis and a Role for Testosterone Combination Therapy in Men

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1RA and triple (GIP)/GLP‐1RA/glucagon agonists achieve placebo‐subtracted weight loss of 15% to 22%. Their long‐term value depends on how well the weight loss is maintained and on the composition of weight loss, not only
Michael Zitzmann, Zsolt Bosnyak, Richard Jones, Monica Caliber   +3 more
wiley   +1 more source

Association Between the GMI/HbA1c Ratio and Microvascular Complications in Type 1 Diabetes: A Multicenter Cross‐Sectional Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective To clarify whether the glucose management indicator (GMI)/glycated haemoglobin (HbA1c) ratio (GMI/HbA1c ratio) is an independent predictor of microvascular complications in Type 1 diabetes (T1D). Design and Methods Multicentre, cross‐sectional, observational study including subjects with T1D with at least 5 years of evolution, users ...
Sandra Herranz‐Antolín, María Asunción Martínez‐Brocca, Gloria Cánovas‐Molina, Aurora Aragón‐Alonso, Miguel Brito‐Sanfiel, Jose Ignacio Martínez‐Montoro, Virginia Bellido, Sharona Azriel, María del Carmen López‐García, Cristina Tejera, Amparo Bartual, Verónica Perea, Pedro José Pines, Antonio J. Amor, Óscar Moreno‐Pérez, Rebeca Reyes‐García, Gema López‐Gallardo, María Durán‐Martínez, Cristina Serrano, Rosa Márquez‐Pardo, Noemí González‐Pérez de Villar, Manuel Gargallo, Estefanía Santos, Pedro Pujante, Jessica Ares, Diego Bellido, Ignacio Conget, Fernando Gomez‐Peralta   +27 more
wiley   +1 more source