Results 151 to 160 of about 93,717 (263)

Validation of the Milan Score Using Prolonged Wireless PH Monitoring

Alimentary Pharmacology &Therapeutics, EarlyView.
The Milan Score, a high‐resolution manometry‐derived tool, predicts pathological GERD on 96‐h wireless pH monitoring with high specificity and positive predictive value, maintaining robust discriminative performance across both typical and atypical symptom profiles and outperforming single HRM parameters as a standalone manometric parameter.
Stefano Siboni, Jiurgen Mema, Trevor McCarthy, Roberta De Maron, Matthew K. Schroeder, Marco Sozzi, Carlo Galdino Riva, Emanuele Asti, C. Prakash Gyawali   +8 more
wiley   +1 more source

Risk Prediction of Early‐Onset Hepatocellular Carcinoma: Derivation and Validation in a Nationwide Young Adult Cohort

Alimentary Pharmacology &Therapeutics, EarlyView.
In 1,756,593 young adults, a generalized boosted survival model predicted incident HCC with strong discrimination (1‐year AUROC 0.945; 5‐year 0.825). The 1‐year horizon uniquely targets an imaging‐silent, pre‐diagnosis window, showing routine clinical signals can flag otherwise undetectable risk.
Seogsong Jeong, Gi‐Ae Kim, Heejoon Jang, Dong Hyeon Lee, Sae Kyung Joo, Keon Wook Kang, Hwamin Lee, Won Kim   +7 more
wiley   +1 more source

Various dimensions of sexual self‐concept in middle‐aged men after vasectomy: a matched analysis

BJU International, EarlyView.
Objectives To compare men with and without vasectomy across four dimensions of sexual self‐concept—toughness, body image, sexual self‐esteem, and perceived pressure with regard to sexuality—and to examine differences in sexual behaviour and psychosocial factors.
Lilly J. Schmalbrock, Camille Nöckel, Valentin H. Meissner, Matthias Jahnen, Stefan Schiele, Martina Kron, Helga S. Schulwitz, Andreas Dinkel, Jürgen E. Gschwend, Kathleen Herkommer   +9 more
wiley   +1 more source

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, EarlyView.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, EarlyView.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Potential Value of Weight-Adjusted Waist Circumference Index in Estimating the Prevalence of Prehypertension and Hypertension in an Elderly Chinese Population. [PDF]

J Clin Hypertens (Greenwich)
Zhu R, Du Z, Lin X, Wang Z, Guo X.
europepmc   +1 more source

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton, Elham Kamran, Lehana Thabane, Peter Yin, Rebecca Christensen   +4 more
wiley   +1 more source

Risk of progression to type 2 diabetes or regression to normoglycaemia among Ghanaians with prediabetes living in Ghana and the Netherlands: The RODAM prospective study

Diabetic Medicine, EarlyView.
Abstract Introduction Evidence shows that ethnicity affects the risk of progression of prediabetes to type 2 diabetes(T2D) or regression to normoglycaemia However, little is known about progression rates among sub‐Saharan African populations or whether geographical context affects risk variations.
Emmanuel Bannerman‐Williams, Yacoba Atiase, Bert‐Jan H. van den Born, Felix Patience Chilunga, Eva van der Linden, Karlijn A. C. Meeks, Erik Beune, Charles Agyemang, Charles Frederick Hayfron‐Benjamin   +8 more
wiley   +1 more source

Does the Combination of Abdominal Obesity and Vitamin D Deficiency Increase the Risk of Death in Individuals Aged 50 or Older? Evidence From the ELSA Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Despite the known association between abdominal obesity (AO) and vitamin D deficiency, it remains unclear whether this combination is associated with higher mortality risk. We investigated whether the coexistence of AO and vitamin D deficiency elevates the risk of death.
Joyce da Silva Milliati, Thaís Barros Pereira da Silva, Roberta de Oliveira Máximo, Mariane Marques Luiz, Sara Souza Lima, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre   +7 more
wiley   +1 more source

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women [PDF]

Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sat Byul Park, Sun Ha Jee
core