Results 171 to 180 of about 93,717 (263)

Rates of, Reasons for, and Reactions to Discontinuation of GLP‐1 Receptor Agonists: A Narrative Review

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT GLP‐1RAs are increasingly used for their glucose‐lowering and weight‐management effects, but many patients discontinue them. In this narrative review we aim to review real‐world, quantitative and qualitative GLP‐1RA discontinuation, adherence, and persistence evidence as it aligns with an established conceptual framework for understanding ...
Henry D. Heisey, L. Parker Gregg, Christopher D. Verrico, Dennis T. Villareal, Terri L. Fletcher   +4 more
wiley   +1 more source

Weight-Adjusted Waist Index as a Novel Predictor of Chronic Obstructive Pulmonary Disease: Evidence from NHANES 2013-2018

International Journal of COPD
Hongjin Wang,1,* Weiming Chen,2,* Feilong Guo,2,* Zengkai Xu,1 Xin Luo,1 Jiahuang Wu,1 Yong Zhu,2 Zhisheng Wang1 1Department of Cardiovascular Surgery, Longyan First Affiliated Hospital of Fujian Medical University, Longyan ...
Wang H, Chen W, Guo F, Xu Z, Luo X, Wu J, Zhu Y, Wang Z   +7 more
doaj  

Oral Semaglutide 25 mg Versus Orforglipron 36 mg in Obesity: A Population‐Adjusted Indirect Treatment Comparison

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to indirectly compare the effects of oral semaglutide 25 mg versus orforglipron 36 mg on body weight loss, other cardiometabolic biomarkers, and tolerability in adults with overweight (body mass index [BMI] ≥ 27 kg/m2 and at least one obesity‐related complication) or obesity (BMI ≥ 30 kg/m2), without diabetes, using data ...
Wojciech Michalak, Martin Bøg, Theiss Bendixen, Rohan Chowdhury, Phoebe Cowley, Christian Laugesen, Naveen Rathor, Robert F. Kushner   +7 more
wiley   +1 more source

Proteomic Profiling Captures Residual Cardiovascular Risk Beyond the PREVENT Model in Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 2–3

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome reflects complex pathobiological interactions among metabolic disorders, kidney injury, and cardiovascular disease (CVD). Stages 2 and 3 represent critical phases of disease progression characterised by high pathological heterogeneity.
Xuefei Han, Jiacheng Ding, Jingqian Li, Yiyin Gao, Yunqian Li   +4 more
wiley   +1 more source

Short‐Term Combined Treatment With Tirzepatide and Metformin for Overweight/Obese Chinese Women With Polycystic Ovary Syndrome: A Prospective, Open‐Label, Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to assess the effects of low‐dose tirzepatide combined with metformin (COM) versus metformin (MET) monotherapy in overweight/obese women with polycystic ovary syndrome (PCOS). Materials and Methods Sixty overweight/obese women with PCOS were randomised to the MET group (1000 mg twice daily [BID]) or the COM group (MET ...
Zhuoran Yang, Yuxin Xu, Hu Du, Wenya Liu, Haiyan Chen, Dongfang Liu, Lili Zhang, Cong Wang   +7 more
wiley   +1 more source

Abnormal Glycaemic Fluctuations Associated With Early Microvascular Changes in the Retina and Choroid of Nondiabetic Adults

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between continuous glucose monitoring (CGM)‐derived glycaemic variability indicators and early microvascular changes of the retina and choroid in nondiabetic individuals. Materials and Methods Community‐based individuals at high risk for type 2 diabetes (T2DM) underwent detailed assessments including oral ...
Yan Jiang, Liping Gu, Yuhang Ma, Yuan Qu, Hancong Wan, Kangjia Lv, Qian Zhu, Hao Zhou, Jian Sun, Fei Lu, Xiaowei Li, Yufei Wang, Jian Zhou, Kun Liu, Yufan Wang, Yinchen Shen   +15 more
wiley   +1 more source

Relationship between triglyceride-glucose-derived obesity indices and NAFLD in adolescents: A cross-sectional study. [PDF]

Medicine (Baltimore)
Deng W, Mei J, Wang A, Yu Q, Pan W, Ding G, Zhou H, Aniwan A, Yu B.   +8 more
europepmc   +1 more source

Association of Long‐Term Trajectories in Obesity Indices With Neuroimaging Metrics and Cognition: A Population‐Based Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Accurate assessment of gradual age‐related weight gain, a common phenomenon, is crucial for identifying brain health risks. This study investigated the associations between long‐term trajectories in obesity indices and brain structure and cognition. Methods This study included 1114 participants from the Kailuan cohort with ≥ 3 follow‐
Yanbo Liang, Zhiming Lu, Xiaoqing Yuan, Mingze Xu, Ying Hui, Shouling Wu, Zhenchang Wang, Ning Wu, Yuntao Wu, Han Lv   +9 more
wiley   +1 more source

Early Pregnancy Central Obesity and Risk of Prenatal and Postpartum Diabetes and Hypertensive Disorders. [PDF]

Diabetes Care
Rosen Vollmar AK, Hedderson MM, Ngo AL, Chehab RF, Peterson AK, Greenberg MB, Liao LD, Ames JL, Ferrara A, Zhu Y.   +9 more
europepmc   +1 more source

Loss of Posterior Occlusal Support Is Associated With Incident Steatotic Liver Disease in a Nationwide Longitudinal Analysis of the JMDC Claims Database

Hepatology Research, EarlyView.
ABSTRACT Aim Steatotic liver disease (SLD), including metabolic dysfunction–associated SLD (MASLD) and metabolic dysfunction–associated alcohol‐related liver disease (MetALD), is a growing global health burden. Although impaired mastication is linked to metabolic disorders, its role in SLD remains unclear.
Takashi Miyano, Taro Kusama, Manami Hoshi‐Harada, Ken Osaka, Kenji Takeuchi   +4 more
wiley   +1 more source