Results 91 to 100 of about 391,469 (311)

Assessment of Knee Joint Proprioception in Weight Bearing and in Non-Weight Bearing Positions in Normal Subjects [PDF]

open access: yes, 2013
Background: Assessment of proprioception isvaluable for identifying proprioceptive deficits.There are several methods to assess the prop-rioception. Joint position sense can be assessedin weight bearing (WB) and non weight bearing(NWB) position of the ...
Amita Mehta   +3 more
core  

The ChIP-seq-defined networks of Bcl-3 gene binding support its required role in skeletal muscle atrophy [PDF]

open access: yes, 2012
NF-kappaB transcriptional activation is required for skeletal muscle disuse atrophy. We are continuing to study how the activation of NF-kB regulates the genes that encode the protein products that cause atrophy. Using ChIP-sequencing we found that Bcl-3,
Jackman, Robert W.   +2 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Trajectories and Predictors of Weight-Bearing and Non-Weight-Bearing Pain in Knee Osteoarthritis: A 9-Year Follow-Up Study

open access: yesJournal of Pain Research
Zi-jun He,1,2,* Jin-tao Wei,1,* Hai-mei Jiang,1 Jin-yong Wang,1 Jiong-yao Lai,1 Shu-qing Li,1 Zhi Chen,1 Qing-lu Luo1– 3 1Department of Rehabilitation Medicine, The Tenth Affiliated Hospital of Southern Medical University (Dongguan People’s ...
He ZJ   +7 more
doaj  

Three-Dimensional Bone Alignment from Cone-Beam Computed-Tomography Scans in Weight-Bearing and Clinical Outcomes Following the Modified Grice–Green Surgical Procedure for Adult Acquired Flatfoot

open access: yesApplied Sciences
Severe adult-acquired flatfoot deformity is widely addressed surgically via the Grice–Green subtalar arthrodesis. Standard radiographic measurements have been reported, but these are limited to planar views.
Giulio Sacchetti   +7 more
doaj   +1 more source

Effect of High-intensity Laser Therapy on Shear-wave Elastography Parameters in Achilles Tendinopathy: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Achilles tendinopathy is a common musculoskeletal occurrence primarily affecting athletes, but the general population is also prone to develop this pathology.
Muskan Bathla   +4 more
doaj   +1 more source

Medium-Long-Term Clinical and Radiographic Outcomes of Minimally Invasive Distal Metatarsal Metaphyseal Osteotomy (DMMO) for Central Primary Metatarsalgia: Do Maestro Criteria Have a Predictive Value in the Preoperative Planning for This Percutaneous Technique? [PDF]

open access: yes, 2018
The purpose of this prospective study was first to evaluate the safety and effectiveness of Minimally Invasive Distal Metatarsal Metaphyseal Osteotomy (DMMO) in treating central metatarsalgia, identifying possible contraindications.
Biz, Carlo   +6 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Weight-Bearing CT for Diseases around the Ankle Joint

open access: yesDiagnostics
Weight-bearing computed tomography (WBCT) enables acquisition of three-dimensional bony structure images in a physiological weight-bearing position, which is fundamental in understanding the pathologic lesions and deformities of the ankle joint. Over the
Jahyung Kim   +3 more
doaj   +1 more source

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