Results 61 to 70 of about 2,912,633 (312)

Weight-Bearing CT for Diseases around the Ankle Joint

Diagnostics
Weight-bearing computed tomography (WBCT) enables acquisition of three-dimensional bony structure images in a physiological weight-bearing position, which is fundamental in understanding the pathologic lesions and deformities of the ankle joint. Over the
Jahyung Kim, Jaeyoung Kim, Saintpee Kim, Young Yi   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The effect of weight-bearing training with visual feedback on balance and prosthetic loading in trans-tibial amputees following vascular disease – a pilot randomized control trial

Annals of Medicine
Purpose Asymmetrical weight-bearing on trans-tibial prosthesis at the initial prosthetic fitting results in a modified gait and secondary disorders. The pilot study will examine the feasibility of the weight-bearing training with visual feedback in trans-
Imre Cikajlo, Jovana Mitić, Helena Burger   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Combining textured insoles and compelled body weight shift improves lower limb function and gait in individuals with stroke: a randomised controlled trial

Human Movement
Purpose To assess the effects of combining textured insoles (TI; plantar somatosensory stimulation) with compelled body weight shift (CBWS) on lower limb motor function, gait, and sensory function in stroke patients.
Adamu Adamu Ahmad, Duangporn Suriyaamarit, Akkradate Siriphorn   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Initial non-weight-bearing therapy is important for preventing vertebral body collapse in elderly patients with clinical vertebral fractures

, 2012
Yoichi KishikawaKishikawa Orthopaedic Clinic, Saga City, Saga, JapanPurpose: The aim of the present conventional observational study was to compare the clinical outcomes of initial non-weight-bearing therapy and conventional relative rest therapy among ...
Kishikawa Y
core  

Defining an Accelerated Rehabilitation Protocol Following Anterior Cruciate Ligament Reconstruction: A Scoping Review

Medicina
Background and Objectives: Accelerated rehabilitation after anterior cruciate ligament reconstruction (ACLR) is widely implemented, yet its definition and distinguishing characteristics remain inconsistently described in the literature.
Maximilian Heinz, Jonathan Lettner, Aleksandra Królikowska, Maciej Daszkiewicz, Sebastian Damm, Nikolai Ramadanov, Roland Becker, Robert Prill   +7 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Trajectories and Predictors of Weight-Bearing and Non-Weight-Bearing Pain in Knee Osteoarthritis: A 9-Year Follow-Up Study

Journal of Pain Research
Zi-jun He,1,2,* Jin-tao Wei,1,* Hai-mei Jiang,1 Jin-yong Wang,1 Jiong-yao Lai,1 Shu-qing Li,1 Zhi Chen,1 Qing-lu Luo1– 3 1Department of Rehabilitation Medicine, The Tenth Affiliated Hospital of Southern Medical University (Dongguan People’s ...
He ZJ, Wei JT, Jiang HM, Wang JY, Lai JY, Li SQ, Chen Z, Luo QL   +7 more
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