Results 171 to 180 of about 737,632 (262)

Association between gestational weight gain and adverse pregnancy outcomes: a systematic review and meta-analysis. [PDF]

Front Glob Womens Health
Ye X, Li P, Shi C.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Metformin in the management of antipsychotic-induced weight gain – why the ‘weight’?

Frontiers in Psychiatry
Ita Fitzgerald, Ita Fitzgerald, Laura J. Sahm, Laura J. Sahm, Laura J. Sahm, Ciara Ní Dhubhlaing, Ciara Ní Dhubhlaing, Sarah O’Dwyer, Jean O’Connell, Jean O’Connell, Jennifer Torrens, Erin K. Crowley   +11 more
doaj   +1 more source

Changes in metabolic risk factors and gut microbiota during weight gain in male first-year college athletes. [PDF]

Physiol Rep
Tanaka N, Hirano K, Kitagawa F, Murakami H, Akima H.   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause.

JAMA Netw Open
Xia T, Haslam DE, Eliassen AH, Manson JE, Sun Q, Willett WC, Bhupathiraju SN, Zhang C, Hu FB.   +8 more
europepmc   +1 more source

Interdialytic blood pressure is independent of weight gain and correlated with serum angiotensin II levels in adults. [PDF]

Physiol Rep
Diaz A, Delgado B, Argaiz ER, Vega O, Correa-Rotter R, Rodriguez-Iturbe B.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Candidate blood biomarkers linked with feed intake efficiency and weight gain in sheep. [PDF]

Sci Rep
Osonowo O, Goldansaz SA, Lei Y, Gellatly D, Jawad H, Borzouie S, Markus S, Miar Y, Thompson S, Manafiazar G.   +9 more
europepmc   +1 more source