Results 191 to 200 of about 775,314 (263)

Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced weight gain in female mice. [PDF]

Nat Commun
Li L, Hernandez CC, Gimenez LE, Xu B, Dahir NS, Peisley A, Wu Z, Chen M, Serrato A, Wan R, Swati, Birnbaum SG, Cone RD, Liu C.   +13 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Gut microbiome in preterm infants with different weight gain outcomes. [PDF]

Gut Microbiol
Daniel SG, Matute JD, Dhudasia MB, Rosewood H, Wilson NG, Patterson A, Hao F, Underwood M, Bittinger K, Mukhopadhyay S.   +9 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Gestational weight gain status and body satisfaction among Kurdish women: a cohort study. [PDF]

BMC Pregnancy Childbirth
Abdulwahid RG, Ahmed HM.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Revealing Hidden Patterns: Harnessing Correspondence Analysis to Explore Maternal Lifestyle Profiles and Gestational Weight Gain. [PDF]

Nutrients
Alemayohu MA, Loperfido F, Cazzoletti L, Zanolin ME, El Masri D, Bianco I, Ferrara C, Cerbo RM, Ghirardello S, Maccarini B, Sottotetti F, Garofoli F, Angelini M, Monti MC, Cena H, De Giuseppe R.   +15 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Addressing Tamoxifen-Associated Weight Gain: Lifestyle and Pharmacotherapy Options. [PDF]

J Adv Pract Oncol
Fore-Williams L, Distler M.
europepmc   +1 more source