Results 201 to 210 of about 737,632 (262)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Developing a Polygenic Risk Score for Weight Gain in People Treated for Psychosis-Application in a Real-World Setting. [PDF]

Hum Psychopharmacol
Heald A, Illangasekera Y, Loureiro CM, Shakespeare M, Jameson A, Phillipson A, Reynolds GP, Dalton C.   +7 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Association of gestational weight gain with adverse pregnancy outcomes across body mass index categories for twins in China. [PDF]

Front Reprod Health
Zhu H, Jia X, Yang L, Peng X, Zou K, Xiang Y, Xie D.   +6 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

The effects of antenatal interventions on gestational weight gain in low and middle-income countries: a systematic review. [PDF]

BMJ Glob Health
Aggrey PA, Nguyen CH, Asghari-Kamrani A, Fawzi WW, Wang D.   +4 more
europepmc   +1 more source

Gestational weight gain and birth outcomes in a large Canadian cohort of pregnant persons with inflammatory bowel disease. [PDF]

Crohns Colitis 360
Nguyen DM, Tandon P, Govardhanam V, Hanna Y, Tao JJ, Cepo J, Maxwell C, Huang VW.   +7 more
europepmc   +1 more source

Wheat Flour Intake Promotes Weight Gain and Metabolic Changes in Mice. [PDF]

Mol Nutr Food Res
Matsumura S, Marutani M, Nousou E, Murakami N, Mizobata S, Fujisawa M, Fujiwara M, Iki N, Horie S, Yamato Y, Yamamoto A, Fujitani M, Fujikawa T, Ishibashi C, Takenaka S.   +14 more
europepmc   +1 more source

Cafeteria diet exposure, and not weight gain propensity, impacts gut microbiota of rats - a within laboratory meta-analysis. [PDF]

Gut Microbes Rep
Bhagavata Srinivasan SP, Kendig MD, Hasebe K, Kaakoush NO, Morris MJ, Leigh SJ.   +5 more
europepmc   +1 more source

Anatomical Atlas of Kinase Responsiveness to Weight Gain: Adipose Depot Reprogramming in Diet-Induced Adiposity. [PDF]

Metabolites
Lee WH, Kipp ZA, Pauss SN, Martinez GJ, Xu M, Hinds TD.   +5 more
europepmc   +1 more source