Results 201 to 210 of about 758,503 (311)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Changes in metabolic risk factors and gut microbiota during weight gain in male first-year college athletes. [PDF]

Physiol Rep
Tanaka N, Hirano K, Kitagawa F, Murakami H, Akima H.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Interdialytic blood pressure is independent of weight gain and correlated with serum angiotensin II levels in adults. [PDF]

Physiol Rep
Diaz A, Delgado B, Argaiz ER, Vega O, Correa-Rotter R, Rodriguez-Iturbe B.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause.

JAMA Netw Open
Xia T, Haslam DE, Eliassen AH, Manson JE, Sun Q, Willett WC, Bhupathiraju SN, Zhang C, Hu FB.   +8 more
europepmc   +1 more source

Identifying research priorities for gestational weight gain in India: A national exercise. [PDF]

Indian J Med Res
Manna S, Roy SP, Lyngdoh T, Chowdhury R, Khandelwal S, Thiruvengadam R, Gupta Y, Nair M, Sharma KA, Radhika AG, Mukherjee A, Kulkarni B, Chandhiok N, Bhatnagar S, Yajnik CS, Mukherjee R.   +15 more
europepmc   +1 more source

Excessive gestational weight gain in the first trimester among women with normal glucose tolerance and resulting neonatal adiposity

, 2016
Jami L. Josefson, Hannah R. Simons, Dinah M. Zeiss, Boyd E. Metzger   +3 more
openalex   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source