Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Impact of Maternal Weight and Gestational Weight Gain on Postpartum Hemorrhage and Adverse Outcomes: A Case-Control Study. [PDF]
Chawanpaiboon S, Lucksanapanij M.
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Postnatal Rapid Weight Gain of Japanese Infants Based on the World Health Organization Child Growth Standards. [PDF]
Akaboshi I.
europepmc +1 more source
Gestational weight gain according to treatment in gestational diabetes: a systematic review and meta-analysis [PDF]
Carolina de Freitas Alves Amaral-Moreira +5 more
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Digital Lifestyle Interventions to Support Healthy Gestational Weight Gain: Scoping Review.
Otte RA, Duracher L, Demir O, Spelt HAA.
europepmc +1 more source
Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation. [PDF]
Carolan A +21 more
europepmc +1 more source

