Results 51 to 60 of about 2,645,661 (354)

A comparison of finishing strategies to fixed slaughter weights for Holstein Friesian and Belgian Blue × Holstein Friesian steers [PDF]

open access: yes, 2010
peer-reviewedCattle finishing strategies may involve feeding a high energy diet throughout or following a period of moderate growth. The objective of this study was to compare Holstein Friesian (HF) and Belgian Blue × Holstein Friesian (BB) steers (24 ...
Keane, Michael G.
core  

Effect of adjunctive ranitidine for antipsychotic-induced weight gain: A systematic review of randomized placebo-controlled trials [PDF]

open access: yes, 2017
This study was a meta-analysis of randomized controlled trials (RCTs) of ranitidine as an adjunct for antipsychotic-induced weight gain in patients with schizophrenia.
Chen, Rui   +13 more
core   +3 more sources

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

Relation between age of menarche and gestational weight gain: a cross-sectional study in Brazil [PDF]

open access: yesRevista Brasileira de Saúde Materno Infantil
Objectives: to investigate the relation between age at menarche and gestational weight gain. Methods: cross-sectional study, with 2609 women from “Projeto VIVER: desfechos em saúde nos períodos perinatal e neonatal” (VIVER Project: “Health outcomes in ...
Dayse Ramos Cassiano   +3 more
doaj   +1 more source

The unidentified hormonal defense against weight gain.

open access: yesPLoS Biology, 2020
Human biology has evolved to keep body fat within a range that supports survival. During the last 25 years, obesity biologists have uncovered key aspects of physiology that prevent fat mass from becoming too low.
Jens Lund   +3 more
doaj   +1 more source

Long-term evaluation of a UK Community Pharmacy-Based Weight Management Service [PDF]

open access: yes, 2020
Obesity increases the risk of cardiovascular disease, type 2 diabetes and cancer, reducing both the quality and quantity of life. Consequently, government healthcare costs are significant. A greater than 5% reduction in weight has been shown to result in
Evans, Gareth, Wright, David
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

The effectiveness of a weight maintenance intervention for adults with intellectual disabilities and obesity: a single stranded study [PDF]

open access: yes, 2015
Background: The evidence base for weight management programmes incorporating a weight loss and a weight maintenance phase for adults with intellectual disabilities (ID) is limited.
Hankey, Catherine   +2 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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