Results 91 to 100 of about 745,851 (257)

Sustainable development of fuel cell using enhanced weighted mean of vectors algorithm. [PDF]

open access: yesHeliyon, 2023
Singla MK   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Weighted integral inequalities with the geometric mean operator

open access: yesJournal of Inequalities and Applications, 2002
The geometric mean operator is defined by A precise two-sided estimate of the norm for , is given and some applications and extensions are pointed out.
Stepanov Vladimir D, Persson Lars-Erik
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

DISTRIBUTION OF SOME HEAVY METALS IN THE NEWI.Y RECLAIMED SOILS OF EL-KHATTARA AS AFFECTED BY THE LANDUSE PERIOD [PDF]

open access: yesEgyptian Journal of Desert Research, 2005
M. Abdel-Rahman   +2 more
doaj   +1 more source

Solutions to mean curvature equations in weighted standard static spacetimes

open access: yesElectronic Journal of Differential Equations, 2020
In this article, we study the solutions for the mean curvature equation in a weighted standard static spacetime, $\mathbb{P}_f^n\times_\rho\mathbb{R}_1$, having a warping function $\rho$ whose weight function f does not depend on the parameter $t\in ...
Henrique F. de Lima   +2 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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