Results 81 to 90 of about 256,372 (245)
Control Charts Based on Weighted Sums
In a continuous production process, samples of fixed size are taken at regular intervals of time and a statistic $X_n$ is computed from the $n$th sample, $n = 1,2, \cdots$. In this paper, we study process inspection schemes which stop the production and take corrective action with $N = \text{first} n \geqq 1$ such that $\sum^n_{i=1} c_{n-i} X_i \geqq h$
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Estimating Sum by Weighted Sampling [PDF]
We study the classic problem of estimating the sum of n variables. The traditional uniform sampling approach requires a linear number of samples to provide any non-trivial guarantees on the estimated sum. In this paper we consider various sampling methods besides uniform sampling, in particular sampling a variable with probability proportional to its ...
Rajeev Motwani, Rina Panigrahy, Ying Xu
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
A note on the max-sum equivalence of randomly weighted sums of heavy-tailed random variables
This paper investigates the asymptotic behavior for the tail probability of the randomly weighted sums Pn k=1 θkXk and their maximum, where the random variables Xk and the random weights θk follow a certain dependence structure proposed by Asimit and ...
Yang Yang +3 more
doaj
Improved weighted sum estimation of total radiated power at W7-X
As magnetic confinement devices move toward higher fusion powers, moderating the heat load to the plasma-facing components becomes increasingly challenging. Efficient power dissipation can be achieved through control of the plasma radiation.
G. Partesotti +6 more
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The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Study on disruption management scheduling problem of flow shop under supply chain environment
This paper presents a disruption scheduling model for an environment of proportional two-machine no-wait flow shop. To achieve the objects of minimization of weighted sum of makespan and minimization of weighted sum of tardiness, we introduce a revised ...
Bo Hong Guang +3 more
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Large Deviation Probabilities for Weighted Sums
Taking as our point of departure the methods and results in a 1960 paper of Bahadur and Ranga Rao, we derive asymptotic representations of large deviation probabilities for weighted sums of independent, identically distributed random variables. The main theorem generalizes the Bahadur-Ranga Rao result in the absolutely continuous case.
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Landslide Risk Assessments through Multicriteria Analysis
Natural risks comprise a whole range of disasters and dangers, requiring comprehensive management through advanced assessment, forecasting, and warning systems. Our specific focus is on landslides in difficult terrains.
Fatma Zohra Chaabane +4 more
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