Results 51 to 60 of about 450,020 (291)

Improving likelihood-based inference in control rate regression [PDF]

, 2017
Control rate regression is a diffuse approach to account for heterogeneity among studies in meta-analysis by including information about the outcome risk of patients in the control condition.
Guolo, Annamaria
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A New Gain-Phase Error Pre-Calibration Method for Uniform Linear Arrays

Sensors, 2023
In this paper, we consider the gain-phase error calibration problem for uniform linear arrays (ULAs). Based on the adaptive antenna nulling technique, a new gain-phase error pre-calibration method is proposed, requiring only one calibration source with ...
Chang Liu, Xiao Tang, Zhi Zhang
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

High Precision Compensation for a Total Reflection Prism Laser Gyro Bias in Consideration of High Frequency Oscillator Voltage

Sensors, 2019
Traditional compensation methods based on temperature-related parameters are not effective for complex total reflection prism laser gyro (TRPLG) bias variation.
Yuanbo Tao, Sihai Li, Jiangtao Zheng, Feng Wu, Qiangwen Fu   +4 more
doaj   +1 more source

Review of the mathematical foundations of data fusion techniques in surface metrology [PDF]

, 2015
The recent proliferation of engineered surfaces, including freeform and structured surfaces, is challenging current metrology techniques. Measurement using multiple sensors has been proposed to achieve enhanced benefits, mainly in terms of spatial ...
Ai C, Barker R M, Boudjemaa R, De Boor C, D𝚤ez D C, Fabio R, GmbH W, Golub G H, Hansen C D, Hao C, Hemsley R, Inhull, ISO 25178-6, ISO 25178-604, ISO/DIS 25178-606, JDL, Jiang X, Kjer H M, Leica Microsystems, Low K-L, Mathworks, Raid I, Ramasamy S K, Rasmussen C E, Rasmussen C E, Schabenberger O, Schmit J, Seeger S, Shekhar S, Strutz T, Sun W, Wang J, Weisstein E W, Yamany S M, Yan-Mei C   +34 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Additive modeling systems to simultaneously predict aboveground biomass and carbon for Litsea glutinosa of agroforestry model in tropical highlands

Forest Systems, 2023
Aim of study: To develop and cross-validate simultaneous modeling systems for estimating components and total tree aboveground biomass and carbon of Litsea glutinosa in an agroforestry model with cassava.
Bao HUY, Nguyen Q. KHIEM, Nguyen Q. TRUONG , Krishna P. POUDEL, Hailemariam TEMESGEN   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source