Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Computationally efficient optimum weighting function for vector quantization of LSF parameters
We propose a new weighting function which is computationally simple and an approximation to the theoretically derived optimum weighting function shown in the literature.
Chatterjee, Saikat, Sreenivas, TV
core
Local feature weighting in nearest prototype classification [PDF]
The distance metric is the corner stone of nearest neighbor (NN)-based methods, and therefore, of nearest prototype (NP) algorithms. That is because they classify depending on the similarity of the data.
Isasi, Pedro +2 more
core +1 more source
Piecewise Weighting Function for Collaborative Filtering Recommendation
It is not always reasonable to set a fixed weight value to an attribute (or a variable) because this cannot accurately maintain the similarity between users and leads to decrease the performance of collaborative filtering recommendation algorithms.
Jiaye Li (13491493) +1 more
core +1 more source
Improvement Method of Antenna Negative Sidelobes on Cross Beam Correlation Microwave Radiometer
A weighting method is proposed for the correlation radiation measurement system based on Mills cross array. The Mills cross array achieves high spatial resolution by the product of two orthogonal fan beams. However, the product power pattern of the Mills
Xiaolong Feng +4 more
doaj +1 more source
Identification of Multimodel LPV Models with Asymmetric Gaussian Weighting Function
This paper is concerned with the identification of linear parameter varying (LPV) systems by utilizing a multimodel structure. To improve the approximation capability of the LPV model, asymmetric Gaussian weighting functions are introduced and compared ...
Jie You +6 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Feature weighting techniques for CBR in software effort estimation studies: A review and empirical evaluation [PDF]
Context : Software effort estimation is one of the most important activities in the software development process. Unfortunately, estimates are often substantially wrong. Numerous estimation methods have been proposed including Case-based Reasoning (CBR).
Boyce Sigweni +3 more
core +1 more source
Calibrated Weighting for Small Area Estimation
Calibrated weighting methods for estimation of survey population characteristics are widely used. At the same time, model-based prediction methods for estimation of small area or domain characteristics are becoming increasingly popular.
Chambers, R. L.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

