Results 81 to 90 of about 5,428,070 (308)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A simple derivation of Prelec’s probability weighting function [PDF]

open access: yes
Since Kahneman and Tversky (1979), it has been generally recognized that decision makers overweight low probabilities and underweight high probabilities.
Ali al-Nowaihi, Sanjit Dhami
core  

WAIRS: Improving Classification Accuracy by Weighting Attributes in the AIRS Classifier [PDF]

open access: yes, 2007
AIRS (Artificial Immune Recognition System) has shown itself to be a competitive classifier. It has also proved to be the most popular immune inspired classifier.
Secker, Andrew D.   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

What Determines the Shape of the Probability Weighting Function? [PDF]

open access: yes
When valuing risky prospects, people typically overweight small probabilities and underweight medium and large probabilities, but there is vast heterogeneity in individual behavior. We explore the relationship between person-specific probability weights,
Renate Schubert   +2 more
core  

Probability weighting function in experiment using graphically represented probability information

open access: yesJournal of Human Environmental Studies, 2014
A psychological experiment was conducted to estimate probability weighting function whose stimuli were graphically presented. We conducted a modified experiment of Wu and Gonzalez (1996) study by using graphical representation of lotteries.
Hajime Murakami   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On a Certain Weighted Partition Function [PDF]

open access: yesProceedings of the American Mathematical Society, 1950
Verf. betrachtet von dem in einer früheren Arbeit behandelten Problem [Proc. Am. Math. Soc. 1, 182--191 (1950; Zbl 0037.16903)] den Spezialfall, wo \(\gamma(n)\) die Funktion \(\Lambda(n)\) aus der Primzahltheorie ist. Durch Anwendung der Mellinschen Formel erhält man \[ \log g(s) = -\frac1{2\pi i} \int_{3/2-i\infty}^{3/2+i\infty} \Gamma(z) s^{-z ...
openaire   +2 more sources

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