Results 121 to 130 of about 1,707 (248)

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, EarlyView.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

Chemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke, Carmelo Di Primo, Felix Bernhardt, Alea Schröder, Christian Renzl, Günter Mayer   +5 more
wiley   +1 more source

Hydroprocessing of synthetic kerosene over a non‐sulphided Ni/Al2O3 catalyst: Impact of alcohols and ketones on alkene conversion

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Synthetic jet fuel containing non‐petroleum‐derived kerosene can be produced from synthetic kerosene obtained through processes that include a hydroprocessing step. The potential use of non‐sulphided (reduced) nickel supported on alumina (Ni/Al2O3) was evaluated as an alternative to sulphided catalysts to saturate alkenes in sulphur‐free ...
Garima Chauhan, Felix Link, Cibele Melo Halmenschlager, Arno de Klerk   +3 more
wiley   +1 more source

Carbon monoxide adsorption on NaY zeolite and impregnated with 5% niobium: Characteristics and fixed‐bed study

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic of the CO adsorption process in a fixed‐bed column containing pure NaY zeolite and Nb‐modified NaY (NaY–5%Nb). On the left, breakthrough curves and temperature profiles highlight the dynamic performance and thermal effects during CO adsorption.
Elson Oliveira, Karina Querne de Carvalho, Erika Pereira Felix, Roberta C. P. Rizzo‐Domingues   +3 more
wiley   +1 more source

Congenital scrub typhus: a case report and literature review. [PDF]

Front Pediatr, 2023
Liang P, Su Z, Chen M, Li S.
europepmc   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Magnetic Supraparticles as Identifiers in Single‐Layer Lithium‐Ion Battery Pouch Cells

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
As an alternative to externally applied optical identifiers, magnetic supraparticles (SPs) can be used for contactless identification of lithium‐ion battery pouch cells via magnetic particle spectroscopy. This study validated the integration and detection of magnetic markers in three model scenarios.
Sara Li Deuso, Simon Ziegler, Daniel Weber, Felix Breuer, Daniel Haddad, Stephan Müssig, Andreas Flegler, Guinevere A. Giffin, Karl Mandel   +8 more
wiley   +1 more source

Purification of Li2CO3 Obtained through Pyrometallurgical Treatment of NMC Black Mass from Electric Vehicle Batteries

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Lithium carbonate (Li2CO3) obtained from the black mass of recycled lithium batteries is dissolved in water under controlled conditions to remove lithium fluoride (LiF), which is present at a concentration of 3.08 % by weight. The dissolution is carried out at temperatures below 10 °C, and it has been demonstrated that lower temperatures result in ...
Laura Rosso, Lorena Alcaraz, Olga Rodríguez‐Largo, Félix A. López   +3 more
wiley   +1 more source

Resistance by applied immunology: fabricated typhus epidemic as civil protection in occupied Poland during World War II. [PDF]

Infection
Nunes-Biesiadecka J, Drzewiecka D, Gatermann S, Jantsch J, Fätkenheuer G.   +4 more
europepmc   +1 more source

Selective Modification of the Product Profile of Biocatalytic Hydrolyzed PET via Product‐Specific Medium Engineering

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The product profile of enzymatically hydrolyzed PET can be modified by medium engineering and thereby adapted to a desired product. TPA, MHET or BHET can be forced as the predominant product using a basic pH (blue), 25 % ethylene glycol (EG) and IsPETasewt (green) or ≥25 % EG and LCCICCG (pink), respectively.
Tobias Heinks, Katrin Hofmann, Simon Last, Igor Gamm, Luise Blach, Ren Wei, Uwe T. Bornscheuer, Christof Hamel, Jan von Langermann   +8 more
wiley   +1 more source