Results 71 to 80 of about 1,219,423 (282)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Инфекция и иммунитет, 2016 Acute infectious mononucleosis is a widespread viral disease, which most often manifests in childhood. The development of acute infectious mononucleosis is accompanied by the change of the CD4+/CD8+ T-lymphocytes ratio and the increase of the virus ...
E. N. Filatova +5 more
doaj +1 more source
Employment Outcomes in the Welfare State [PDF]
We examine the implications of tax and subsidy policies for employment in the "three worlds of welfare", Anglo-Saxon, Continental European and Scandinavian. We argue that home production is key to a proper evaluation of the employment outcomes.
Christopher A. Pissarides +1 more
core
The Internal and External Affects of a Governor\u27s State Budget Cuts on the Department of Child Welfare [PDF]
, 2009 State budget cuts reduce the resources available to the Department of Child Welfare. The Child Welfare Unit has had an increase in caseloads and a decrease in workers, resulting in an increase in caseloads for the remaining workers.
Albury, Tara
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
On the frontline of the welfare service state: any possibilities for a practice of citizenship?
Social Work and Society, 2020 The article starts from the broad shift towards active service-oriented welfare states highlighting its underlying ideas and main characteristics in order to discuss critical implications of this mode of welfare state intervention to the notion of social
Urban Nothdurfter
doaj +2 more sources
New labour and reform of the English NHS: user views and attitudes. [PDF]
, 2009 BACKGROUND: The British National Health Service has undergone significant restructuring in recent years. In England this has taken a distinctive direction where the New Labour Government has embraced and intensified the influence of market principles ...
Taylor-Gooby, Peter, Wallace, Andrew
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Regional disparities in health services provision in the European Union.
Finisterra - Revista Portuguesa de Geografia, 2022 Services of general interest (SGI) contribute to the European Union’s objectives, being fundamental to territorial cohesion and convergence, with a preeminent role in rural and peripheral territories.
Pedro Franco, Eduarda Marques da Costa
doaj
PECULIARITIES OF ACUTE RESPIRATORY DISEASES IN PATIENTS WITH ATOPY
Архивъ внутренней медицины, 2015 In the work identified clinical and immunological characteristics of the course of ARVI patients with atopy and assessed the clinical efficacy of transfer factor in patients with severe immune deficiency.
L. O. Ponezheva +2 more
doaj +1 more source