Results 71 to 80 of about 230,838 (295)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Use of Welfare Technology in Elderly Care

open access: yes, 2017
This thesis is an interpretive qualitative research study exploring the use of welfare technology in elderly care. In Norway, health care and social services for elderly people are important parts of the welfare policy.
Woll, Anita
core  

The Stable Equilibrium of Preferential Trade Agreements under Technology Asymmetry

open access: yesEast Asian Economic Review, 2011
This paper examines the optimal policy for trade negotiation in the current multilateral and preferential trade regime. Using a four country oligopoly model with asymmetric technology, we examine the implication of preferential trade agreement on tariff ...
Young-Han Kim , Jae-Duck Kim
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Patent Protection, Innovation Rate and Welfare [PDF]

open access: yes
In the context of international technology transfer from the developed North to the developing South, this paper analyses the impact of the Southern patent protection on the innovation rate in the North and the welfare effect in the South.
Uday Bhanu Sinha
core  

A systematic review of the potential uses of on-animal sensors to monitor the welfare of sheep evaluated using the Five Domains Model as a framework

open access: yes, 2019
Fogarty, ES ORCiD: 0000-0003-0212-0156This systematic review explores the use of on-animal sensors in sheep and their potential application in objective welfare monitoring.
GM Cronin (9855005)   +11 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

‘Developments in New Technology & Implications for Seafarers’ Welfare’

open access: yes, 2011
A report published today by the International Committee on Seafarers’ Welfare (ICSW) has found that seafarers’ access to the latest communications technology is taking a back seat because of high investment costs and ports’ concerns about security ...
Swift, Olivia
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Aging in Place: Dealing with Breakdown of Welfare Technology

open access: yes, 2013
This paper is about breakdown that occurs within the contextual frame of elderly aging in place by support of innovative welfare technology. The paper presents use of Activity Theory as a constructive framework to explore laypeople experiences with ...
Woll, Anita
core  

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