Results 51 to 60 of about 159,407 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Social Work and Society, 2005 This paper explores the similarities and differences between Denmark and Australia in adopting welfare reform activation measures in the field of employment services. In Australia and Denmark the discourse of welfare reform centres the 'activation' of
Greg Marston
doaj +2 more sources
European Psychiatry, 2021 Introduction Disruptive behaviours underpin the most prevalent and costly psychiatric disorders in youth including ADHD and conduct disorder. Yet the association between childhood behavioural problems and economic and social outcomes in adulthood are ...
F. Vergunst +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Race to the bottom: Labor forces, policy and immigration in Vietnam
International Review of Economics & FinanceThis paper examines the interplay between labor market dynamics, internal migration, and institutional reforms in shaping income inequality across 63 Vietnamese provinces from 2012 to 2022. Drawing on the race-to-the-bottom framework, we employ a Two-Way
Fei Fan, Ha Van Trung
doaj +1 more source
Universal versus economically polarized change in age at first birth : a French–British comparison [PDF]
, 2009 France and the United Kingdom in the 1980s and 1990s represented two contrasting institutional models for the integration of employment and motherhood: The ‘universalistic’ regime type offering subsidized child-care and maternity-leave benefits at all ...
Adsera +47 more
core +3 more sources
At the heart of the Nordic occupational welfare model: Occupational welfare trajectories in Sweden and Denmark [PDF]
Social Policy & Administration, 2018 AbstractSweden and Denmark are countries with a strong tradition of the involvement of labor market partners in welfare policies, and this begs the question whether this influences the development of occupational welfare. This article depicts the reasons for, and the development of, occupational welfare, especially in relation to pensions, sickness ...
openaire +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Immigrant Inclusion in the Safety Net: A Framework for Analysis and Effects on Educational Attainment [PDF]
, 2015 Across states, there is substantial variation in the degree to which immigrants and their children are offered public assistance. We present a theoretical framework for analyzing the effects of policy decisions about immigrant inclusion.
Condon, Meghan +2 more
core +1 more source