Results 61 to 70 of about 159,407 (303)
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Background While a vast amount of studies confirm the social reproduction of class and status from one generation to the next, less is known about the role of health in the child generation for these processes. Research has shown that particularly mental
Evelina Landstedt +4 more
doaj +1 more source
The ecology of social interactions in online and offline environments [PDF]
The rise in online social networking has brought about a revolution in social relations. However, its effects on offline interactions and its implications for collective well-being are still not clear and are under-investigated.
Antoci, Angelo +3 more
core +1 more source
Introduction – Managing Welfare Expectations and Social Change: Policy Responses in Asia [PDF]
The question whether Asian welfare types can be classified as distinctly ‘productivist’ has remained subject to lively debates: in East Asia, the recent implementation of social rights-based public policy innovations – including working family support ...
Kühner, Stefan +2 more
core +2 more sources
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
The trajectories of eugenics [PDF]
Introduzione al numero monografico di Contemporanea intitolato "Present days-eugenics"
Betta, E.
core
Imagined, prescribed and actual text trajectories: the ‘problem’ with case notes in contemporary social work [PDF]
Drawing on a text-oriented action research ethnography of the writing practices of UK-based social workers, this paper focuses on a key but problematic aspect of everyday, professional textual practice – the production of “case notes.” Using data drawn ...
Lillis, Theresa
core +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source

