Results 81 to 90 of about 1,420,108 (278)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

From Utopian Socialism to Modern Welfare States: The Evolutionary Trajectory of Social Welfare Thought

International Journal of Education and Humanities
This study charts the progression of social welfare ideology from 19th-century utopian socialism to contemporary welfare state configurations. It initiates with a critical appraisal of utopian socialist tenets-advocated by Owen, Fourier, and Saint-Simon-underscoring communalism, social cohesion, and equitable resource allocation.
openaire   +1 more source

Welfare effects from food price shocks and land constraints in Niger

Journal of Agriculture and Food Research
Households in low-income and food insecure nations such as Niger are vulnerable to food price shocks as a large portion of their budgets are spent on calories derived from cereals and other staples.
Manzamasso Hodjo, Timothy J. Dalton, Tebila Nakelse   +2 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

CLUSTER ANALYSIS OF MULTIVARIATE PANEL DATA ON DATA CONTAINING OUTLIERS

Barekeng
One clustering method for panel data is K-Means Longitudinal (KML), which considers only a single trajectory per subject over time. To address this limitation, KML was extended into K-Means Longitudinal 3D (KML3D), which enables clustering of joint or ...
Kristuisno Martsuyanto Kapiluka, Hari Wijayanto, Anwar Fitrianto   +2 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Trajectory of thirst intensity and distress from admission to 4-weeks follow up at home in patients with heart failure

Patient Preference and Adherence, 2018
Nana Waldréus,1 Misook L Chung,2 Martje HL van der Wal,3,4 Tiny Jaarsma5,6 1Department of Neurobiology, Division of Nursing, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden; 2College of Nursing, University of Kentucky ...
Waldréus N, Chung ML, van der Wal MHL, Jaarsma T   +3 more
doaj  

Being an au pair in London: Young Spanish women’s employment trajectories and strategies in regimes of gender and precariousness

Papers
The global economic crisis that began in 2008 led to major cuts to the welfare state in Spain and across Europe (Gambino, 2018), affecting key areas such as health, education, social care and youth employment.
Almudena Cortés, Fernando Barbosa
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Airport resilience to large-scale events: the case of Pulkovo Airport

Urban, Planning and Transport Research
This study applies an established social cost–benefit analysis (CBA), combined with sequential shock scenarios (COVID-19 and the post-2022 sanctions) and Monte Carlo sensitivity analysis, to evaluate the welfare robustness and recovery dynamics of the ...
Boris A. Lodiagin, Varvara V. Nazarova, Carlos J. Rincon   +2 more
doaj   +1 more source