Results 101 to 110 of about 18,121,258 (292)

Probiotic-infused Mixed Polymeric Nanoparticles Co-incubated with Antibiotics: An Alternative Approach to Combat Drug-resistant Bacteria

open access: yesThe EuroBiotech Journal
The frequent rise of antibiotic-resistant bacteria is due to the increasing use of antibiotics in the healthcare system. Probiotics could offer a potential alternative, although their efficacy tends to be diminished in the presence of antibiotics ...
Thirumalai Anbazhagan   +4 more
doaj   +1 more source

Well-oriented magnesium hydroxide nanoplatelets coating with high corrosion resistance and osteogenesis on magnesium alloy

open access: yesJournal of Magnesium and Alloys
Magnesium alloys are nontoxic and promising as orthopedic metallic implants, but preparing a biocompatible Mg(OH)2 layer with high corrosion protection ability remains challenging.
Ya Shu   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Corrosion Resistance of Well Steel in a Supercritical Carbon Dioxide Environment in Geothermal Systems Utilizing Depleted Hydrocarbon Reservoirs

open access: yesEnergies
This study evaluates the corrosion behavior of N80 production tubing steel under high-temperature, high-pressure (HTHP) conditions representative of CO2-based geothermal exploitation in depleted hydrocarbon reservoirs.
Mateusz Masłowski   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A unified equivalent-resistance framework for smart-well inflow-control technologies in reservoir–wellbore coupled simulation

open access: yesFrontiers in Earth Science
Long horizontal wells equipped with flow-control devices (FCDs) are widely used to redistribute inflow and delay water breakthrough in heterogeneous reservoirs. However, inflow control devices (ICDs), autonomous inflow control devices (AICDs), and inflow
Qingshuang Jin   +6 more
doaj   +1 more source

A well test model for composite reservoir with resistance force on interface

open access: yes, 2013
Tazhong No.1 gas field is a typical vug-fractured carbonate gas condensate reservoir with the characteristics of high heterogeneity and complex geological and dynamics.
孙贺东, 刘曰武, Shi Y
core   +1 more source

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