Results 91 to 100 of about 18,121,258 (292)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effects of Exergames and Resistance Training on Well-Being in Older Adults: A Randomized Clinical Trial [PDF]

Geriatrics, Gerontology and Aging
OBJECTIVE: To analyze the effects of an exergame-based training compared to resistance training on the quality of life and symptoms of depression in older adults. METHODS: This was a two-arm, non-blinded, randomized clinical trial.
Vandrize Meneghini, Eduardo Hauser, Camilo Luis Monteiro Lourenço, Aline Rodrigues Barbosa   +3 more
doaj   +1 more source

Milwaukee, Wisconsin 2023

, 2023
Covenants mapped as of Mar. 2 2023Other title Milwaukee County racial covenants, early results Notes This map shows the progress to date of the Mapping Racism and Resistance project in identifying housing deeds that included racial covenants.
Mapping Racism and Resistance
core  

Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance [PDF]

, 2005
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Endocrine responses to low‐load blood flow restricted and high‐load resistance exercise in well‐trained males

Physiological Reports
The present study compared acute testosterone (T), cortisol (C), epinephrine (EPI), norepinephrine (NE), and 22 kDa growth hormone (GH‐22 kDa) responses following low‐load resistance exercise with blood flow restriction (LL‐BFR) and traditional high‐load
Drake A. Eserhaut, Joseph M. DeLeo, Jessica A. Provost, Andrew C. Fry   +3 more
doaj   +1 more source

Influence of acid systems on bottomhole zone decolmatization and set cement stability

Фізика і хімія твердого тіла
The state of the bottomhole zone during drilling was assessed on the example of well No. 47 Stynava. Based on the study of the impact of drilling fluid on the filtration and capacitance characteristics of the core material, it was found that the ...
Ye.M. Stavychnyi, S.M. Rudyi, Ya.M. Femiak, B.A. Tershak, S.A. Piatkivskyi, M.M. Klymyuk, V.V. Kindrat   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source