Results 71 to 80 of about 18,121,258 (292)

Living Well with Chronic Conditions: chronic disease self-management in Oregon

This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Ceased with 2009Mode of access: Internet from the Oregon ...

core   +2 more sources

Antimicrobial drug use and resistance in Europe [PDF]

, 2008
Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that ...
Grundmann, Hajo, Goossens, Herman, Ferech, Matus, Zarb, Peter, Sande-Bruinsma, Nienke van de, Verloo, Didier, Tiemersma, Edine, Monen, Jos, European Antimicrobial Resistance Surveillance System and European Surveillance of Antimicrobial Consumption Project Groups   +8 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Phytogenic synthesis of silver nanoparticles using Lepidium sativum: Characterization and evaluation of its antibacterial potential

Environment Conservation Journal
In this study, an eco-friendly approach was used to successfully synthesize silver nanoparticles (AgNPs) from Lepidium sativum aqueous leaf extract.
Chetna Chauhan, Navneet Bithel
doaj   +1 more source

Mitigating employee resistance and achieving well-being in digital transformation

Information Technology & People
Purpose Digital transformation is a complex and continuous process that presents significant challenges for companies and employees. Employee resistance, a factor often cited for the failure of digital initiatives, hinders these initiatives and contributes to stress, affecting employee well-being – a connection ...
Alena Valtonen, Mira Holopainen
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Development of a Capacitance-Resistive Model Accounting for Shut-in Wells

, 2018
Capacitance-Resistance Model (CRM) is a nonlinear signal processing model which provides information about the interwell communication and reservoir heterogeneity. This method is a simple data-driven model which enables reservoir engineers to use injection and production historical data to perform history matching, forecast the future performance and ...
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Numerical modeling of vacuum preloading incorporating time-dependent well resistance and depth-attenuated vacuum with a reference-grid-mapped well-boundary correction

Yantu gongcheng xuebao
Existing consolidation for soft soil ground improved by theories on vacuum preloading often fail to simultaneously account for the smear effect, time-dependent well resistance degradation due to clogging, and non-uniform vacuum pressure transmission ...
JIA Mincai 1, 2, WANG Chaoyang 1, 2, WENG Kailiang 1, 2
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source