Results 21 to 30 of about 436,672 (299)

Supporting People Data Linking Programme: Linked data research into the impact of housing-related support on use of healthcare services

open access: yesInternational Journal of Population Data Science, 2023
Objectives With an annual budget of over £120 million, the Welsh Government Supporting People Programme provided housing-related support to help vulnerable people to avoid homelessness and live as independently as possible.
Tony Whiffen, Kathryn Helliwell
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Good practice guide for sector and standard setting bodies (guidance) [PDF]

open access: yes, 2010
"This guide is for sector and standards setting bodies to assist them in determining the demand for Welsh language skills, Welsh translations of national occupational standards (NOS) and vocational qualifications (VQs) through the medium of Welsh ...

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Seeing the wood for the trees: clustering for competitiveness in the Welsh timber sector

open access: yesWelsh Economic Review, 2006
Seeing the wood for the trees: clustering for competitiveness in the Welsh timber ...
David Pickernell   +3 more
doaj   +1 more source

Songs and Identity in Welsh Patagonia [PDF]

open access: yesStudia Ethnologica Pragensia, 2023
Over the centuries there have been a number of attempts, for economic, political and religious reasons, to create Welsh settlements overseas. The most successful of these, in terms of longevity at least, and perhaps the best known of all Welsh emigration
E. Wyn James
doaj  

Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor

open access: yesCommunications Biology, 2022
Rational engineering of human spermine oxidase yields crystallizable structures and the design of an allosteric inhibitor.
Elsie Diaz   +17 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Welsh-medium education strategy : annual report 2010–11 [PDF]

open access: yes, 2011
"The Welsh-medium Education Strategy was published by the Welsh Government in April 2010 in fulfilment of a One Wales commitment to ‘create a national Welsh-medium Education Strategy to develop effective provision from nursery through to further and ...

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Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Psychological types of bilingual and monolingual female undergraduate students in Wales [PDF]

open access: yes, 2010
The aim of this study was to complete the psychological type profiles of bilingual (fluent Welsh speakers) and monolingual (nonWelsh-speakers) students in Wales.
Craig, Charlotte L., Francis, Leslie J.
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