Results 21 to 30 of about 54,241 (248)
Critical Stages, 2021 This article, written in two voices, one Khasi, one Welsh, revisits the process of devising Performing Journeys, a theatre production that toured India and Wales in 2019–20.
Lisa Lewis, Lapdiang Syiem
doaj
The Welsh Government Flying Start Data Linking Project
International Journal of Population Data Science, 2019 Background with rationale Flying Start is the Welsh Government’s (WG) flagship Early Years programme for families with children aged less than 4 years of age.
Laura Herbert +3 more
doaj +1 more source
BMC Public Health, 2017 Background While existing research indicates that housing improvements are associated with health improvements, less is known about the wider social and health benefits of meeting national housing standards, as well as those of their specific constituent
Wouter Poortinga +3 more
doaj +1 more source
Towards Adaptive, human-centric lighting: Limitations of Subjective Measures and a multimodal framework [PDF]
E3S Web of ConferencesIndoor lighting plays a crucial role in shaping occupant comfort, health, and productivity, as they spend 90% of their time indoors. While intensive research on adaptive lighting technologies is ongoing, most current strategies are still primarily based ...
Kavuthimadathil Sreelakshmi +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Songs and Identity in Welsh Patagonia [PDF]
Studia Ethnologica Pragensia, 2023 Over the centuries there have been a number of attempts, for economic, political and religious reasons, to create Welsh settlements overseas. The most successful of these, in terms of longevity at least, and perhaps the best known of all Welsh emigration
E. Wyn James
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor
Communications Biology, 2022 Rational engineering of human spermine oxidase yields crystallizable structures and the design of an allosteric inhibitor.
Elsie Diaz +17 more
doaj +1 more source