Results 41 to 50 of about 436,672 (299)

Breaking the mould? Whiteness, masculinity, Welshness, working-classness and rugby league in Wales [PDF]

, 2012
Traditionally, rugby in Wales has meant rugby union, the once-amateur, fifteen-a-side code that has a long history of working-class, male involvement in the Valleys of South Wales (Williams, G., 1985).
Spracklen, C, Spracklen, K
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Evaluation of the feasibility of 3D scanning to provide individualized compression therapies among healthy volunteer subjects

Veins and Lymphatics, 2018
Not ...
Michael Clark, Sue Hagelstein, Nia Jones
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The expenditure impacts of individual higher education institutions (HEIS) and their students on the Welsh economy : homogeneity or heterogeneity? [PDF]

, 2010
This paper replicates the analysis of Scottish HEIs in Hermannsson et al (2010a) for the case of Wales in order to provide a self-contained analysis that is readily accessible by those whose primary concern is with the regional impacts of Welsh HEIs ...
Hermannsson, Kristinn, Lisenkova, Katerina, McGregor, Peter, Swales, John   +3 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

All-Wales Survey of Bullying in Schools (research document) [PDF]

, 2010
"The first comprehensive survey of bullying in schools across Wales took place in Summer 2009 and gathered information from around 7,400 pupils. The survey, commissioned by the Welsh Assembly Government and undertaken by the People and Work Unit, gives a

core  

AD|ARC (Administrative Data Agri-Research Collection): Linking Individual, Household and Farm Business Data for Sociodemographic Research on Farming Households

International Journal of Population Data Science
Objective To understand the socio-demographic characteristics and structure of farming households in Wales who receive subsidies compared to non-farming rural households.
Sian Morrison-Rees, Laura Madden, Matthew Curds, Paul Caskie, Rachael Loftus   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

NP would like to meet GF: A Welsh Adjectival Construction [PDF]

, 2008
In this article we examine a Welsh adjectival construction which superficially looks simple but on closer examination proves to be somewhat challenging. The construction contains an NP constituent whose GF status is far from clear.
Mittendorf, I, Sadler, L
core  

Pathways between Probation services and Substance Misuse Treatment Services in Wales

International Journal of Population Data Science
This report investigates the number of individuals who successfully transition into treatment services after a Community Sentence treatment Requirement (CSTR) for an alcohol treatment requirement or a drug rehabilitation requirement in Wales.
Sam Fallick, Josh Dixon, Silvia Colonna
doaj   +1 more source