Results 51 to 60 of about 436,672 (299)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Welsh-medium Education Strategy (information document) [PDF]

open access: yes, 2010
"This Strategy sets out the ambition of the Welsh Assembly Government for a country where Welsh-medium education and training are integral parts of the education nfrastructure.

core  

Networking Historic Environmental Standards to Address Modern Challenges for Sustainable Conservation in HBIM

open access: yesApplied Sciences, 2020
Awareness of the logic and context of original (and subsequent) design priorities is critical to informing decisions relating to valorisation, repair, refurbishment, energy retrofit or re-use of built heritage.
Oriel Prizeman   +3 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Word length distributions in modern Welsh prose texts. [PDF]

open access: yes, 2003
This paper examines the distribution of word lengths in 12 prose texts written in modern Welsh (a P-Celtic language). The texts belong to the genres of new articles and Bible translation.
Wilson, Andrew
core  

Impact of the Welsh Government Flying Start programme on children’s BMI and immunisation uptake

open access: yesInternational Journal of Population Data Science
Flying Start (FS) is the Welsh Government’s targeted Early Years programme for families with children under 4 years of age who live in some of the most disadvantaged areas of Wales. The programme aims to mitigate the impact of poverty which is linked
Silvia Colonna, Kathryn Helliwell
doaj   +1 more source

Wales: (Still) a Problem of Translation? Language Choice in Wales at the End of the Anglo-Welsh Era

open access: yesIperstoria, 2016
In 1996 the poet  R. S. Thomas claimed that ‘my country, Cymru, to be understood presents a problem of translation, and if it is to maintain a separate and valuable identity, it must continue to do so.’ Thomas, a native speaker of English, and a self ...
David Newbold
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

In the Blood or in the Water? Exploring predictors of Welsh language ability among young people

open access: yesInternational Journal of Population Data Science
Objectives Cymraeg 2050 outlines the Welsh Government’s strategy for the promotion and the facilitation of the use of the Welsh language and seeks to have a million Welsh speakers by 2050.
Rhys Davies, Katy Huxley, John Poole
doaj   +1 more source

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