Results 61 to 70 of about 436,672 (299)

Welsh Government Flying Start Programme Evaluation Using Linked Data

open access: yesInternational Journal of Population Data Science, 2018
Introduction Flying Start (FS) is the Welsh Government’s (WG) flagship Early Years programme for families with children aged less than 4 years of age.
Sarah Lowe   +3 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Taking action on child poverty : consultation paper [PDF]

open access: yes, 2008
This consultation document presents the Welsh Assembly Government’s proposals for taking action on child poverty. This includes making new legislation to introduce a duty on public agencies in respect of child poverty, to provide free childcare places ...

core  

Challenges in Early Years data and their implications on programme evaluations

open access: yesInternational Journal of Population Data Science
The Welsh Government funds a wide range of Early Years programmes to both support parents to remain in work and children’s social, emotional and educational development.
Silvia Colonna, Kathryn Helliwell
doaj   +1 more source

Surgical Site Infection in Spinal Operations a Tertiary Centre Review of 4557 Consecutive Procedures over 5 Years

open access: yesGlobal Spine Journal, 2016
Background Surgical Site Infection (SSI) is a potential inherent risk of any surgical intervention. SSI can pose significant consequences especially in spinal surgery.
Hassan Fawi   +4 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Education and lifelong learning statistics (consultation document) [PDF]

open access: yes, 2010
Welsh Assembly Government consultation that seeks views from users of education and lifelong learning statistics on our current suite of outputs and a number of specific ...

core  

Présentation des hebdomadaires de langue galloise

open access: yesLa Bretagne Linguistique, 1992
This paper will provide a brief overview of the historical development of Welsh and its current situation. After an analysis of the sociolinguistic history of Welsh over the last half millennium, the cultural habits of Welsh speakers, particularly with ...
Humphrey Lloyd Humphreys
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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