Results 61 to 70 of about 436,672 (299)
Welsh Government Flying Start Programme Evaluation Using Linked Data
Introduction Flying Start (FS) is the Welsh Government’s (WG) flagship Early Years programme for families with children aged less than 4 years of age.
Sarah Lowe +3 more
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Taking action on child poverty : consultation paper [PDF]
This consultation document presents the Welsh Assembly Government’s proposals for taking action on child poverty. This includes making new legislation to introduce a duty on public agencies in respect of child poverty, to provide free childcare places ...
core
Challenges in Early Years data and their implications on programme evaluations
The Welsh Government funds a wide range of Early Years programmes to both support parents to remain in work and children’s social, emotional and educational development.
Silvia Colonna, Kathryn Helliwell
doaj +1 more source
Background Surgical Site Infection (SSI) is a potential inherent risk of any surgical intervention. SSI can pose significant consequences especially in spinal surgery.
Hassan Fawi +4 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Education and lifelong learning statistics (consultation document) [PDF]
Welsh Assembly Government consultation that seeks views from users of education and lifelong learning statistics on our current suite of outputs and a number of specific ...
core
Présentation des hebdomadaires de langue galloise
This paper will provide a brief overview of the historical development of Welsh and its current situation. After an analysis of the sociolinguistic history of Welsh over the last half millennium, the cultural habits of Welsh speakers, particularly with ...
Humphrey Lloyd Humphreys
doaj +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source

