Results 71 to 80 of about 106,969 (295)

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

The European Union Settlement Scheme Data Linkage Project in Wales: Findings relating to mental health and education

International Journal of Population Data Science
Objective  Following the UK’s exit from the European Union (EU) a settlement scheme was introduced for EU nationals currently living in the UK to apply to continue living in the UK.
Ffion Lloyd-Williams, Matthew Curds, Stephen Drinkwater   +2 more
doaj   +1 more source

How deep is your immersion? Policy and practice in Welsh-medium preschools with children from different language backgrounds

, 2014
A challenge noted in a number of endangered language contexts is the need to mix second-language (L2) learners of the target language with first-language (L1) speakers of that language in a less planned way than is found in the two-way immersion approach.
T. Hickey, Gwyneth Lewis, C. Baker
semanticscholar   +1 more source

The UK Biobank resource with deep phenotyping and genomic data

Nature, 2018
The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data collected on approximately 500,000 individuals from across the United Kingdom, aged between 40 and 69 at recruitment.
Clare Bycroft, C. Freeman, D. Petkova, G. Band, L. Elliott, Kevin Sharp, A. Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O’Connell, A. Cortes, S. Welsh, Alan Young, Mark Effingham, G. McVean, S. Leslie, N. Allen, P. Donnelly, J. Marchini   +18 more
semanticscholar   +1 more source

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

Arthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro, Karen Durrant, William G Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H Humphreys   +6 more
wiley   +1 more source

The Complex Governance and Public Engagement Challenge of the AD|ARC Project: Research to Support Farming Communities Across the UK

International Journal of Population Data Science
Objectives Administrative Data | Agricultural Research Collection is a complex research project involving four nations, a mixture of business-level, household-level and person-level data, and diverse stakeholders.
Laura Madden, Rachael Loftus, Sian Morrison-Rees, Sarah Lowe, Freya Pryce, Paul Caskie   +5 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

Establishment of a National Homelessness Prevention Programme dataset to enable an anonymised longitudinal dynamic cohort based study

International Journal of Population Data Science, 2018
Introduction Welsh Government invests over £120m annually in housing related support to help prevent and tackle homelessness under the ‘Supporting People Programme’. A 2016 data-linkage Feasibility Study indicated health-service utilisation reductions
Sarah Lowe, Rhodri Johnson, Ian Jones, Sian Morrison-Rees   +3 more
doaj   +1 more source

Investigation of Laser Ablation and Brush Pre‐Treatments for AlCu Cold Roll Bonding in Oxygen‐Free Conditions

Advanced Engineering Materials, EarlyView.
It is shown that laser ablation pretreatment under oxygen‐free conditions enables copper–aluminium bonding at significantly lower deformation degrees and improved properties compared to mechanical brushing. Laser ablation further increases interface contact area and induces favourable residual stress states and microstructural compatibility ...
Khemais Barienti, Finn‐Lennard Janthur, Selina Raumel, Sascha Jan Zimmermann, Sarah Seffer, René Gustus, Sebastian Herbst, Marc C. Wurz, Ludger Overmeyer, Wolfgang Maus‐Friedrichs, Hans Jürgen Maier, Florian Nürnberger   +11 more
wiley   +1 more source