Results 111 to 120 of about 21,295 (232)
Genes to Cells, Volume 31, Issue 4, July 2026.We identified a Mis4 cohesin loader mutant that is specifically defective in chromatin axis formation and homologous recombination while retaining normal sister chromatid cohesion. The mis4‐LR mutant, carrying the L1150S and R1159G amino acid substitutions, exhibited reduced interaction between Mis4 and Rec8, suggesting a meiosis‐specific role for the ...
Takeshi Sakuno +3 more
wiley +1 more source
Gender, Work &Organization, Volume 33, Issue 4, Page 1347-1358, July 2026.ABSTRACT Women continue to face systemic barriers to exercising leadership in the music industry. This article critically examines Keychange, a transnational initiative that seeks to transform the industry through talent development advocacy and leadership training for women and gender‐diverse individuals. Drawing on participant interviews and situated
Matina Magkou +2 more
wiley +1 more source
Journal of Clinical Periodontology, Volume 53, Issue 7, Page 990-1004, July 2026.ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo +11 more
wiley +1 more source
Revista Argentina de Radiología, 2011 A pesar de que la asociación entre útero didelfo, hemivagina obstruida y agenesia renal homolateral (síndrome de Herlyn-Werner-Wünderlich) ha sido reportada en la literatura ginecológica, no es familiar al especialista en diagnóstico por imágenes, en ...
Jorge Ahualli +4 more
doaj
Subterranean environments contribute to three‐quarters of classified ecosystem services
Biological Reviews, Volume 101, Issue 3, Page 1582-1605, June 2026.ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola +30 more
wiley +1 more source
WRN regulates pathway choice between classical and alternative non-homologous end joining
Nature Communications, 2016 Werner Syndrome is an accelerated aging disorder marked by genome instability, large deletions and telomere fusions, hallmarks of aberrant DNA repair.
Raghavendra A. Shamanna +5 more
doaj +1 more source
A Case of Werner Syndrome with Endophthalmitis Onset 10 Years after Cataract Surgery
, 2013 Werner 症候群は老人様顔貌,強皮症様皮膚変化,若年性白内障を特徴とする疾患である.発症は100 万人あたり3～45 人とされている.今回,われわれは白内障術後10 年以上経過したにも関わらず強膜創の閉鎖不全が感染の原因と考えられる眼内炎の症例(41 歳,男性)を経験した.Werner 症候群には白内障を合併することが多く,術後も創傷治癒は遅延しやすいため感染のリスクが高い.眼科的な長期の経過観察が必要と考えた.Werner syndrome is a disease characterized ...
Chikuda, Makoto +8 more
core
Estrogen Prevents Senescence through Induction of WRN, Werner Syndrome Protein
, 2010 Werner syndrome is a well-known human progeria. It has been revealed that loss of human WRN is a causal factor of this disease. Since pathological features of Werner syndrome resemble those of menopausal women and become apparent during puberty, we ...
Sun-Hye Lee +3 more
core +1 more source
Parent/caregiver needs during pediatric genome‐wide sequencing: A scoping literature review
Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.Abstract The integration of genome‐wide sequencing (GWS) including whole‐exome and whole‐genome sequencing, has transformed pediatric diagnostics, yet the needs of parents and caregivers during this process remain insufficiently explored. This scoping review aims to synthesize current knowledge on parental and caregiver needs across the GWS process in ...
Priyanka Murali, Joon‐Ho Yu
wiley +1 more source
Nature Communications, 2016 Werner syndrome is a progeroid disease characterised by genetic instability due to mutations to the WRN helicase/exonuclease. Here the authors define a novel Ku binding motif (KBM) and show that two such motifs facilitate the involvement of WRN in DNA ...
Gabrielle J. Grundy +7 more
doaj +1 more source