Results 131 to 140 of about 21,295 (232)
Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome
, 2010 Background: The ATP-competitive p38α MAPK inhibitor VX-745 exhibits an exquisite kinase selectivity profile, is effective in blocking p38 stress signaling in Werner syndrome dermal fibroblasts, has efficacy in clinical trials and may have therapeutic ...
Rokicki, Michal Jaroslaw +13 more
core +1 more source
Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.ABSTRACT After introducing nirsevimab during the 2024/2025 respiratory syncytial virus (RSV) season in Germany, RSV activity in infants under 1 year dropped by 50% in primary care and 50%–70% in secondary care. Inpatients under 6 months showed the greatest reduction.
Wei Cai +14 more
wiley +1 more source
Werner Syndrome Protein and DNA Replication
, 2018 Werner Syndrome (WS) is an autosomal recessive disorder characterized by the premature development of aging features. Individuals with WS also have a greater predisposition to rare cancers that are mesenchymal in origin.
Shibani Mukherjee +5 more
core +1 more source
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley +1 more source
Magnetic resonance imaging diagnosis of Herlyn-Werner-Wunderlich syndrome
, 2017 Herlyn-Werner-Wunderlich syndrome (HWW) is a triad of didelphys uterus, obstructed hemivagina, and ipsilateral renal agenesis. It is a combined anomaly of Mullerian and mesonephric ducts.
Taruna Yadav, Padam Parmar
core +1 more source
Shaping future forests: how can ecophysiology support climate‐smart forest management?
New Phytologist, Volume 250, Issue 5, Page 2778-2813, June 2026.Summary Climate change, particularly the associated increase in extreme events and disturbances, threatens the numerous environmental, social, and economic benefits that forests provide, both locally and globally. Heat and drought pose significant risks to forest ecosystems; the anticipated future climate is expected to exacerbate this trend ...
Arthur Gessler +18 more
wiley +1 more source
Emotions in Meaning‐Making: Toward a Sociological Theory of Cathexis
Sociological Forum, Volume 41, Issue 2, Page 308-319, June 2026.ABSTRACT The role of emotion in meaning‐making remains undertheorized in cultural sociology. This article argues that emotions and affect are intrinsic to meaning‐making and proposes cathexis—the attachment of emotions generated in social interaction to objects, symbols, and ideas—as the fundamental mechanism by which emotions co‐constitute cultural ...
Dmitry Kurakin
wiley +1 more source
Breast cancer in a Hispanic patient with Werner syndrome. [PDF]
J Radiol Case Rep, 2023 Santos MM +4 more
europepmc +1 more source