Results 271 to 280 of about 2,574,835 (312)
Some of the next articles are maybe not open access.
Geriatrics and Gerontology International, 2019
An investigator‐initiated clinical study was carried out to evaluate the therapeutic potency of SR‐0379 for the treatment of leg ulcers in patients with Werner syndrome.
Hironori Nakagami +2 more
exaly +2 more sources
An investigator‐initiated clinical study was carried out to evaluate the therapeutic potency of SR‐0379 for the treatment of leg ulcers in patients with Werner syndrome.
Hironori Nakagami +2 more
exaly +2 more sources
Dermatology, 1971 The symptoms of Werner’s Syndrome are reported by means of 2 cases. The importance of an endocrinological and ophthalmological examination of patients with ‘systemic sclerosis’ is demonstrated.
openaire +2 more sources
Australian and New Zealand Journal of Medicine, 1977
A case of Werner syndrome is reported. The patient was prematurely old, had skin atrophy, characteristic posterior subcapsular cataracts and prepubertal primary hypogonadism. Additional ocular features compatible with premature ageing included presbyopia, arcus seniles and diminished tear flow.
S K, Samantray +3 more
openaire +2 more sources
A case of Werner syndrome is reported. The patient was prematurely old, had skin atrophy, characteristic posterior subcapsular cataracts and prepubertal primary hypogonadism. Additional ocular features compatible with premature ageing included presbyopia, arcus seniles and diminished tear flow.
S K, Samantray +3 more
openaire +2 more sources
Dermatologic Clinics, 1995
Werner's syndrome is a rare autosomal recessive disorder that affects connective tissue throughout the body. The genetic basis is not yet known, although many laboratory abnormalities have been reported. The manifestations are widespread, and many organs may prematurely undergo changes usually associated with aging.
Noreen A. Lemak +2 more
openaire +2 more sources
Werner's syndrome is a rare autosomal recessive disorder that affects connective tissue throughout the body. The genetic basis is not yet known, although many laboratory abnormalities have been reported. The manifestations are widespread, and many organs may prematurely undergo changes usually associated with aging.
Noreen A. Lemak +2 more
openaire +2 more sources
Pathology of the Werner Syndrome
1985Anatomic-pathological observation remains one of the fundamental approaches to the understanding of multiple system disease of unknown etiology. In this paper, we review the results of such anatomic investigations of necropsies of subjects with the Werner syndrome, including five cases (all Japanese subjects) that we have personally autopsied, one of ...
Goro Asano +5 more
openaire +3 more sources
Werner's syndrome as “Hyaluronuria”
Clinica Chimica Acta, 1975Abstract Although excretion of acid glycosaminoglycans into urine of five patients with Werner's syndrome were within normal limits, the quantity of hyaluronic acid increased in this disease. To this novel finding, a term “Hyaluronuria” was proposed.
Masayuki Tokunaga +4 more
openaire +3 more sources
Werner’s Syndrome and Astrocytoma
Dermatology, 1989Werner’s syndrome, a relatively rare and autosomal recessive disorder, is well known to be characterized by a high frequency of malignant neoplasms. Werner’s syndrome has not infrequently been associated with meningiomas. We report a case of Werner’s syndrome and temporal astrocytoma in a 49-year-old male.
C Procel +4 more
openaire +2 more sources
New England Journal of Medicine, 1997
Figure 1. A 37-year-old man was admitted to the hospital because of hoarseness and progressive difficulty in walking. The patient's face had the characteristic beak-like appearance of Werner's syndrome (left panel). Examination disclosed juvenile cataracts, scleroderma-like skin changes, hair loss, deficiency of adipose tissue, and sensory neuropathy ...
openaire +2 more sources
Figure 1. A 37-year-old man was admitted to the hospital because of hoarseness and progressive difficulty in walking. The patient's face had the characteristic beak-like appearance of Werner's syndrome (left panel). Examination disclosed juvenile cataracts, scleroderma-like skin changes, hair loss, deficiency of adipose tissue, and sensory neuropathy ...
openaire +2 more sources
Archives of Ophthalmology, 1974
To the Editor. —In the July issue of theArchives(90:53-56, 1973), Drs. Bullock and Howard reported a case of Werner syndrome. I find the diagnosis unconvincing because of the number of atypical features, which are as follows: Age of presentation. Cataract is commonly present by the age of 20, and by the age of 30 causes severe visual impairment.
openaire +3 more sources
To the Editor. —In the July issue of theArchives(90:53-56, 1973), Drs. Bullock and Howard reported a case of Werner syndrome. I find the diagnosis unconvincing because of the number of atypical features, which are as follows: Age of presentation. Cataract is commonly present by the age of 20, and by the age of 30 causes severe visual impairment.
openaire +3 more sources
Neuropathology of the Werner Syndrome [PDF]
, 1985 In his original report, Werner (1) described four siblings who had in common shortness of stature, senile appearance, early graying of the hair and appearance of cataracts, skin changes and early cessation of menstruation. Subsequent authors added premature balding, tendency to diabetes mellitus and calcification of blood vessels to this picture ...
openaire +2 more sources