Results 41 to 50 of about 58,427 (224)

Ethological risk factors of West nile infection of wild birds in Senegal [PDF]

, 2007
Serological studies performed in 2003, as well as viral isolations demonstrated that West Nile fever (WNF) was endemic in Senegal (West Africa). Large populations of potentially infected birds fly each year from West Africa to Europe.
Baillon, François, Balança, Gilles, Chevalier, Véronique, Gaidet, Nicolas, Lancelot, Renaud, Lefrançois, Thierry, Reynaud, Pierre, Sylla, S.   +7 more
core  

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, EarlyView.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

West Nile Virus Infection in Travelers Returning to United Kingdom from South Africa

Emerging Infectious Diseases, 2019
West Nile virus (WNV) is an arthropod-transmitted flavivirus that causes West Nile fever and may infrequently cause neuroinvasive disease in humans. We present 2 cases of confirmed WNV infection, 1 of severe encephalitis and 1 of mild febrile illness, in
Vivak Parkash, Kate Woods, Liana Kafetzopoulou, Jane Osborne, Emma Aarons, Katharine Cartwright   +5 more
doaj   +1 more source

Human infections associated with wild birds. [PDF]

, 2008
IntroductionWild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature on pathogens causing human disease that have been ...
Bauchinger, Ulf, Falagas, Matthew E, Kelesidis, Iosif, Kelesidis, Theodoros, Tsiodras, Sotirios   +4 more
core   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Results of the West Nile Fever Agent Monitoring in the Russian Federation in 2019 and the Forecast of Epidemic Situation Development in 2020

Проблемы особо опасных инфекций, 2020
The trend towards an increase in the West Nile fever incidence among the population in the Russian Federation, recorded in the season of 2018, continued and led to a significant increase in the incidence in 2019 (the indicator was 2 times higher than the
E. V. Putintseva, I. O. Alekseychik, S. N. Chesnokova, S. K. Udovichenko, N. V. Boroday, D. N. Nikitin, E. A. Agarkova, A A. Baturin, I. M. Shpak, V. K. Fomina, A. V. Nesgovorova, V. P. Smelyansky, D. V. Viktorov, A. V. Toporkov   +13 more
doaj   +1 more source

Imperative for a health‐centred focus on climate change in radiology

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Summary Climate change negatively impacts individual and population‐level health through multiple pathways, including poor air quality, extreme heat and changes in infectious disease. These health effects will lead to higher health system and medical imaging utilisation.
Omar Taboun, Chloe DesRoche, Kate Hanneman   +2 more
wiley   +1 more source

Conditions for Virus Circulation and Premises for Natural West Nile Fever Foci Formation in the Territory of the Saratov Region

Проблемы особо опасных инфекций, 2013
Local climate change (rise of mean temperatures and amount of precipitation, prolongation of frost-free season) triggers further distribution, and increase in numbers of animals – carriers and vectors of West Nile fever virus in the territory of the ...
A. N. Matrosov, V. N. Chekashov, A. M. Porshakov, S. A. Yakovlev, M. M. Shilov, A. A. Kuznetsov, K. S. Zakharov, T. V. Knyazeva, T. V. Mokrousova, S. I. Tolokonnikova, A. I. Udovikov, T. Yu. Krasovskaya, I. N. Sharova, U. A. Kresova, O. V. Kedrova, N. V. Popov, S. A. Shcherbakova, V. V. Kutyrev   +17 more
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source