Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Breeding for culinary and nutritional quality of common bean (Phaseolus vulgaris L.) in intercropping systems with maize (Zea mays L.) [PDF]
Common bean (Phaseolus vulgaris L.) is widely intercropped with maize (Zea mays L.) in the North of Spain. Breeding beans for multiple cropping systems is important for the development of a productive and sustainable agriculture, and is mainly oriented ...
Rodino A.P. +4 more
doaj
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Forests and the national greenhouse gas inventory of Germany. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]
Since 1995, experiences have been gathered with the calculation of National Greenhouse Gas Inventories in Germany. Because only marginal changes of the total forested area occur in Germany, relevant changes of the balance of greenhouse gases in the ...
Baritz R., Strich S.
doaj
A Comparative Analysis of Initiatives and Adaptation Measures to Climate Change Undertaken in Poland and Western Europe [PDF]
The analysis of the main initiatives for adaptation to climate change in selected countries of Western Europe and Poland relate to key issues mentioned in the strategic documents of the European Commission.
Michalak, Dorota
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The use of the soil map of Belgium in the assessment of landslide risk [PDF]
The analysis is based on a report from the Laboratory of Geomorphology and Remote sensing of the University of Liege concerning Mont-de-l'Enclus hill (Province of Hainaut, 20 kilometers north of the city of Tournai).
Closson D., Engels P., Demaret X.
doaj
Fencing off the east: how the refugee crisis is dividing the European Union [PDF]
An analysis of cultural differences between Eastern and Western Europe in the light of the 2015 refugee ...
Culik, Jan
core
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Contribution of forests and forestry in Finland to mitigate greenhouse effect. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]
Ministry of the Environment is coordinating matters related to the unitéd Nation Framework Convention on Climate Change. National reporting of greenhouse gas inventories for land-use change and forestry category utilises forest inventory results with ...
Karjalainen,T., Maekipaeae R.
doaj

