Results 131 to 140 of about 3,769,094 (311)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Western Brass Quintet, March 21, 1980

open access: yes, 2018
Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, Michigan, March 21, 1980, program no. 267 of the Department of Music's 1979-1980 season.Western Brass Quintet (Donald Bullock and Stephen Jones, trumpet ;
Western Brass Quintet
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Western Carolinian Volume 09 November 27, 1940

open access: yes, 2017
The Western Carolinian is Western Carolina University’s student-run newspaper. The paper was published as the Cullowhee Yodel from 1924 to 1931 before changing its name to The Western Carolinian in ...
Western Carolina University;   +2 more
core  

Western Australia

open access: yesThe Lancet Psychiatry, 2021
Gardiner, Fergus W, Coleman, Mathew
openaire   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Western Brass Quintet, November 22, 1974

open access: yes, 2017
Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 22, 1974, program no. 80 of the Department of Music’s 1974-1975 season.Western Brass Quintet (Donald Bullock, Stephen Jones, trumpets ;
Western Brass Quintet
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Western Brass Quintet, March 14, 1975

open access: yes, 2017
Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, Michigan, March 14, 1975, program no. 187 of the Department of Music's 1974-1975 season.Western Brass Quintet (Donald Bullock, Stephen Jones, trumpets ...
Western Brass Quintet
core  

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