Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu+10 more
wiley +1 more source
A guide to selecting high-performing antibodies for PLC-gamma-2 for use in Western Blot, immunoprecipitation and immunofluorescence. [PDF]
Ruíz Moleón V+9 more
europepmc +1 more source
Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee+14 more
wiley +1 more source
Validation of a novel western blot assay to monitor patterns and levels of alpha dystroglycan in skeletal muscle of patients with limb girdle muscular dystrophies. [PDF]
Rajasingham T+4 more
europepmc +1 more source
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li+7 more
wiley +1 more source
Western Blot as a Confirmatory Test for Lyme Disease
Harvey Artsob
doaj +1 more source
A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence. [PDF]
Fanti R+11 more
europepmc +1 more source
Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim+6 more
wiley +1 more source
A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence. [PDF]
Ruíz Moleón V+7 more
europepmc +1 more source